Protein Info for PfGW456L13_5030 in Pseudomonas fluorescens GW456-L13

Annotation: Septum formation protein Maf

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00172: septum formation protein Maf
  • amino acids 2 to 184 (183 residues), 169.8 bits, E=2.2e-54
• PF02545: Maf
  • amino acids 3 to 186 (184 residues), 202.4 bits, E=2.8e-64

Best Hits

Swiss-Prot: 88% identical to NTPPA_PSEPF: dTTP/UTP pyrophosphatase (Pfl01_0841) from Pseudomonas fluorescens (strain Pf0-1)

KEGG orthology group: K06287, septum formation protein (inferred from 88% identity to pfo:Pfl01_0841)

MetaCyc: 54% identical to nucleoside triphosphate pyrophosphatase YhdE (Escherichia coli K-12 substr. MG1655)
Nucleotide diphosphatase. [EC: 3.6.1.9]; 3.6.1.9 [EC: 3.6.1.9]

Predicted SEED Role

"Septum formation protein Maf" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton

MetaCyc Pathways

• superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (18/18 steps found)
• pyrimidine deoxyribonucleotides de novo biosynthesis I (9/9 steps found)
• superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) (12/14 steps found)
• pyrimidine deoxyribonucleotides de novo biosynthesis III (8/9 steps found)
• pyrimidine deoxyribonucleotides de novo biosynthesis II (5/7 steps found)
• dZTP biosynthesis (3/5 steps found)
• pyrimidine deoxyribonucleotides dephosphorylation (1/3 steps found)
• tunicamycin biosynthesis (2/9 steps found)

KEGG Metabolic Maps

• Nicotinate and nicotinamide metabolism
• Pantothenate and CoA biosynthesis
• Purine metabolism
• Riboflavin metabolism
• Starch and sucrose metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.1.9

Sequence Analysis Tools

See A0A293QWH7 at UniProt or InterPro

Protein Sequence (202 amino acids)

>PfGW456L13_5030 Septum formation protein Maf (Pseudomonas fluorescens GW456-L13)
MKRLYLASGSPRRRELLTQIGVAFCAVSADIDETPLAQESPSAYVERLARGKAEAGRGGV
VSDEPFCVLGADTAVVLDGKILGKPVDQADACAMLTMLSGCEHEVLTAIAVLDGGRCESR
VVTSRVRFRDISREEAAAYWASGEPRDKAGGYGIQGLGAVFVAGLDGSYSAVVGLPLCET
AELLGHFGIPCWQPRNAHQATF