Protein Info for PfGW456L13_4939 in Pseudomonas fluorescens GW456-L13

Annotation: Functional role page for Anaerobic nitric oxide reductase transcription regulator NorR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 516 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF01590: GAF" amino acids 25 to 159 (135 residues), 44.2 bits, see alignment E=1.1e-14 PF13185: GAF_2" amino acids 25 to 160 (136 residues), 33.7 bits, see alignment E=1.7e-11 PF00158: Sigma54_activat" amino acids 194 to 360 (167 residues), 232 bits, see alignment E=1.3e-72 PF14532: Sigma54_activ_2" amino acids 195 to 365 (171 residues), 69.7 bits, see alignment E=1.2e-22 PF00004: AAA" amino acids 218 to 346 (129 residues), 24.9 bits, see alignment E=9.8e-09 PF07728: AAA_5" amino acids 218 to 336 (119 residues), 32.3 bits, see alignment E=3.6e-11

Best Hits

Swiss-Prot: 48% identical to LUXO_VIBC3: Regulatory protein LuxO (luxO) from Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)

KEGG orthology group: K12266, anaerobic nitric oxide reductase transcription regulator (inferred from 90% identity to pfo:Pfl01_4653)

Predicted SEED Role

"Functional role page for Anaerobic nitric oxide reductase transcription regulator NorR" in subsystem Nitrosative stress

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QWS6 at UniProt or InterPro

Protein Sequence (516 amino acids)

>PfGW456L13_4939 Functional role page for Anaerobic nitric oxide reductase transcription regulator NorR (Pseudomonas fluorescens GW456-L13)
MTAKPLLTALLPLVADLSRELPEGERYRRLLEAMRALLPCDAAALLRLDGEWLVPLAVDG
LSTDTLGRRFKVSEHPRFEALLSGPGPTRFAADSDLPDPYDGLVDGLDDHLEVHDCMGCP
LFIDERPWGLLTLDALDPERFEPIELDALQAFASLAAATVNAAERIERLNNRVEDEHQRA
EVYRQASGQQNREMIGQSKAHKRLVEEISLVGGSDLTVLITGETGVGKELVAQAIHAASP
RADKPIISLNCAALPDTLVESELFGHVRGAFTGAMNDRRGKFELANGGTLFLDEVGELSL
TVQAKLLRVLQSGQLQRLGSDQEHQVDVRLIAATNRDLAEEVRSGRYRADFYHRLSVYPL
LVPALRDRGRDVLLLSGYFLEQNRSRMGLNSLRLNSDAQAALLAYDWPGNVRELEHLIGR
SALKALGNCKERPKILSLSAADLDLPGASVETAAEQPAIAAVALVAGDLREATENYQRLL
IGACLERHNNNWASAARELGLDRANLGRMAKRLGMK