Protein Info for PfGW456L13_490 in Pseudomonas fluorescens GW456-L13

Annotation: GGDEF domain protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 639 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 46 to 67 (22 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 91 to 208 (118 residues), 57.2 bits, see alignment E=1.9e-19 PF00989: PAS" amino acids 94 to 198 (105 residues), 34.6 bits, see alignment E=5.2e-12 PF13426: PAS_9" amino acids 98 to 199 (102 residues), 51.8 bits, see alignment E=2.5e-17 PF08447: PAS_3" amino acids 109 to 194 (86 residues), 30.1 bits, see alignment E=1.4e-10 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 209 to 371 (163 residues), 132.2 bits, see alignment E=1.5e-42 PF00990: GGDEF" amino acids 212 to 368 (157 residues), 158.9 bits, see alignment E=2.9e-50 PF00563: EAL" amino acids 390 to 624 (235 residues), 261.4 bits, see alignment E=2.1e-81

Best Hits

KEGG orthology group: None (inferred from 85% identity to pfo:Pfl01_0192)

Predicted SEED Role

"GGDEF domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QEJ4 at UniProt or InterPro

Protein Sequence (639 amino acids)

>PfGW456L13_490 GGDEF domain protein (Pseudomonas fluorescens GW456-L13)
MSATYRDALRAALLYLLLSVVWLQISGYLLNSFFDSSAERLRWQLINGYVWVLFSAGLIF
IARARLLRCLGIGAKLRERDADRMRLRQAAAVFDCTREGVLVTNREGLIVHVNRAFMEIT
GYGCEDVLGQRPNLFKSGRHSPEFYQVMFATLASVGEWSGEIWNRRKSGEIYPQWQTIRL
IHDDYGQPSQYVAVFSDISAIKNSEHELMHLAHHDPLTDLPNRLLFTDRAEQALASAQVH
KRGCALLMIDLDHFKMINDSLGHTIGDQLLKAVAERLGAMFGPGVTLARLGGDEFAILAE
SCPQLVQAAALAQRIIEGLKEPFLIDGHQLSINTSIGISLFPSDALSVEQLLRNADSALF
KAKSAGRNDYALYTEELTAHAQQRVEIAFELRRALDRQELRVYYQPVHDLKSRRLIGVEA
LVRWQHPQRGLVSPAEFIPVAERTGLIAEIDAWVMAQACRQMCQWQQDGVVLSFVAVNVS
SRLFARRELYQQVAQVLRETGLEPAFLELEVTESAVMEDPEVALEQMHRLRELGVRLAID
DFGTGYSSLLRLKRLPVQKLKIDQGFVAGLPWDEDDAAISRVIIALAQSMGMQVHAEGIE
QAEQAEFLLEHDCDLGQGYWFGRPVPAEQLDWMHEPVIV