Protein Info for PfGW456L13_4660 in Pseudomonas fluorescens GW456-L13

Annotation: LysR family transcriptional regulator PA3398

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 289 transmembrane" amino acids 72 to 94 (23 residues), see Phobius details PF00126: HTH_1" amino acids 1 to 44 (44 residues), 41 bits, see alignment 2.2e-14 PF03466: LysR_substrate" amino acids 72 to 272 (201 residues), 199.6 bits, see alignment E=6.1e-63 PF12727: PBP_like" amino acids 141 to 270 (130 residues), 30.1 bits, see alignment E=4.1e-11

Best Hits

Swiss-Prot: 44% identical to YEIE_ECOLI: Uncharacterized HTH-type transcriptional regulator YeiE (yeiE) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 97% identity to pfo:Pfl01_1184)

Predicted SEED Role

"LysR family transcriptional regulator PA3398" in subsystem DNA-binding regulatory proteins, strays

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0P8WV88 at UniProt or InterPro

Protein Sequence (289 amino acids)

>PfGW456L13_4660 LysR family transcriptional regulator PA3398 (Pseudomonas fluorescens GW456-L13)
VSRAAGLLNLSQSAASTSITELERQCSCQLFDRAGKRLSLNALGKQLLPQAVALLDQAKE
IEDLLNGKSGFGSLAVGATLTIGNYLATLLIGSFMQRHPESQVKLHVQNTANIVQQVAHY
EIDLGLIEGDCSHPDIEVQSWVEDELVVFCAPQHPLAKRGTATMEELSHEAWILREQGSG
TRLTFDQAMRHHRTSLNIRLELEHTEAIKRAVESGLGIGCISRLALRDAFRRGSLVPVET
PDLDLARQFYFIWHKQKYQTSAMREFLDLCRAFTAGVQRSDEIVLPTIA