Protein Info for PfGW456L13_4652 in Pseudomonas fluorescens GW456-L13

Annotation: Kup system potassium uptake protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 633 transmembrane" amino acids 20 to 38 (19 residues), see Phobius details amino acids 58 to 78 (21 residues), see Phobius details amino acids 109 to 130 (22 residues), see Phobius details amino acids 150 to 168 (19 residues), see Phobius details amino acids 177 to 199 (23 residues), see Phobius details amino acids 219 to 243 (25 residues), see Phobius details amino acids 255 to 276 (22 residues), see Phobius details amino acids 296 to 321 (26 residues), see Phobius details amino acids 348 to 368 (21 residues), see Phobius details amino acids 375 to 400 (26 residues), see Phobius details amino acids 406 to 424 (19 residues), see Phobius details amino acids 430 to 451 (22 residues), see Phobius details PF02705: K_trans" amino acids 23 to 555 (533 residues), 723.6 bits, see alignment E=7.1e-222

Best Hits

Swiss-Prot: 92% identical to KUP_PSEPF: Probable potassium transport system protein kup (kup) from Pseudomonas fluorescens (strain Pf0-1)

KEGG orthology group: K03549, KUP system potassium uptake protein (inferred from 93% identity to pba:PSEBR_a1137)

MetaCyc: 53% identical to K+:H+ symporter Kup (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-3

Predicted SEED Role

"Kup system potassium uptake protein" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QT93 at UniProt or InterPro

Protein Sequence (633 amino acids)

>PfGW456L13_4652 Kup system potassium uptake protein (Pseudomonas fluorescens GW456-L13)
MGQASSQATDAEHSAVKPIGMLVAAVGVVYGDIGTSPLYTLKEVFSGGYGVPVNHDGVLG
ILALIFWSLIWVVSIKYMMFVLRADNQGEGGIMALTALARRAAAGHAKLRMLLVVCGLIG
AALFYGDSMITPAISVLSAIEGLGLAFEGIDHWVVPLSLVVLVALFLIQRHGTARIGILF
GPIMVTWFLVLGALGVYGISQHPEVLEAMNPMWGVRFFMVHPGMGVTILGAVVLALTGAE
ALYADMGHFGRKPIARAWFILVLPALVLNYFGQGALLLGDPEAARNPFYLLAPSWALIPL
VGLSTLATVIASQAVISGAFSLTRQAIQLGYIPRMHIRHTSSAEQGQIYIGAVNWALMVG
VILLVIGFESSGALASAYGVAVTGTMLMTTILVSAVMLLLWKWPPIFAVPILFGFMLVDG
LYFAANVPKIVQGGAFPVIAGFALFVLMTTWKRGKQLLVERIDEGGLPLPIFISSIAVQP
PHRVQGTAVFLTARPDAVPHALLHNLLHNQVLHEQVVLLTVVYEDIPRVPPNRRFEVDSY
GEGFFRVILHFGFTDEPDVPQALKLCHLDELDFSPMRTTYFLSRETVIASKLEGMSRWRE
ALFAFMLQNANGNLRFFNLPLNRVIELGTQVEM