Protein Info for PfGW456L13_4639 in Pseudomonas fluorescens GW456-L13

Annotation: Histidine ABC transporter, ATP-binding protein HisP (TC 3.A.1.3.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 254 PF00005: ABC_tran" amino acids 19 to 178 (160 residues), 123.6 bits, see alignment E=9.4e-40

Best Hits

Swiss-Prot: 69% identical to AOTP_PSEAE: Arginine/ornithine transport ATP-binding protein AotP (aotP) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K10017, histidine transport system ATP-binding protein [EC: 3.6.3.21] (inferred from 94% identity to pfo:Pfl01_1206)

Predicted SEED Role

"Histidine ABC transporter, ATP-binding protein HisP (TC 3.A.1.3.1)" in subsystem Arginine and Ornithine Degradation (TC 3.A.1.3.1)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.21

Use Curated BLAST to search for 3.6.3.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QVL4 at UniProt or InterPro

Protein Sequence (254 amino acids)

>PfGW456L13_4639 Histidine ABC transporter, ATP-binding protein HisP (TC 3.A.1.3.1) (Pseudomonas fluorescens GW456-L13)
MYKLTIEGLHKSYGDHEVLKGVSLKAKTGDVISLIGASGSGKSTFLRCINFLEQPNDGAM
SLDGQNIRMIKDRHGMHVADANELQRIRTRLAMVFQHFNLWSHMTVLENITMAPRRVLGC
DRKEAEDRARRYLDKVGLAPRVADQYPAFLSGGQQQRVAIARALAMEPEVMLFDEPTSAL
DPELVGEVLKVIQGLAEEGRTMIMVTHEMSFARKVSSQVLFLHQGLVEEEGAPEEVLGNP
KSERLKQFLSGNLK