Protein Info for PfGW456L13_459 in Pseudomonas fluorescens GW456-L13

Annotation: Efflux transporter, RND family, MFP subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 367 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 36 to 353 (318 residues), 233.3 bits, see alignment E=1.7e-73 PF16576: HlyD_D23" amino acids 55 to 261 (207 residues), 46.6 bits, see alignment E=2.6e-16 PF13437: HlyD_3" amino acids 172 to 262 (91 residues), 33.6 bits, see alignment E=5.5e-12

Best Hits

KEGG orthology group: None (inferred from 84% identity to pfo:Pfl01_0230)

Predicted SEED Role

"Efflux transporter, RND family, MFP subunit"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293PWP2 at UniProt or InterPro

Protein Sequence (367 amino acids)

>PfGW456L13_459 Efflux transporter, RND family, MFP subunit (Pseudomonas fluorescens GW456-L13)
MVVPGFKVVMALSVVTLLTACDEKKPVQEYLPRVFVQVVKPADYAVPVTLTGDIQARVQT
ELSFRVGGKIIQRSVDVGDRVTAKQVLARLDPKDLQTNVDSAQAQVVAEQARVTQSAAAF
VRQQKLLPKGYTSQSEYDSAQATLHSSQSALSAAKAQLANAKDQLSYTALIADAPGIITE
RQAEVGQVVQATMPIFSLARDGDRDAVFNVYESLLAEKPRDHTIVLSLVDNPAIKTTGTV
REITPAVSAQSGTVQVKVGLDKLPDGMQLGSVVSATASGSGKSVIELPWSALTKNISAPA
VWIVDDKGKAQLHSVTVGRYLTGKVIISGGLKDGDKVIIAGGQLLHPDMEVEIAENTYKD
LTWGAKP