Protein Info for PfGW456L13_4509 in Pseudomonas fluorescens GW456-L13

Annotation: Thiol peroxidase, Bcp-type (EC 1.11.1.15)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00578: AhpC-TSA
  • amino acids 5 to 133 (129 residues), 123.9 bits, E=3.9e-40
• PF08534: Redoxin
  • amino acids 7 to 139 (133 residues), 54 bits, E=1.7e-18

Best Hits

Swiss-Prot: 54% identical to BCP_XANCP: Peroxiredoxin Bcp (bcp) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)

KEGG orthology group: K03564, peroxiredoxin Q/BCP [EC: 1.11.1.15] (inferred from 93% identity to pfo:Pfl01_1369)

MetaCyc: 39% identical to thiol peroxidase (Escherichia coli K-12 substr. MG1655)
1.11.1.15-RXN [EC: 1.11.1.24]

Predicted SEED Role

"Thiol peroxidase, Bcp-type (EC 1.11.1.15)" in subsystem Thioredoxin-disulfide reductase (EC 1.11.1.15)

KEGG Metabolic Maps

• Glutathione metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.15

Use Curated BLAST to search for 1.11.1.15 or 1.11.1.24

Sequence Analysis Tools

See A0A293QV84 at UniProt or InterPro

Protein Sequence (157 amino acids)

>PfGW456L13_4509 Thiol peroxidase, Bcp-type (EC 1.11.1.15) (Pseudomonas fluorescens GW456-L13)
MAVAIDQPVADFQAPATSGQTVSLAGLKGKQVVIYFYPKDSTPGCTTEGQGFRDQYAAFK
AANTEVFGVSRDSLKSHENFKCKQEFPFELISDKDEAICQLFDVIKLKKLYGKEYMGVDR
STFLIDANGVLRQEWRGVKVPGHVDAVLAAAQALNKA