Protein Info for PfGW456L13_4461 in Pseudomonas fluorescens GW456-L13

Annotation: Lipid A export ATP-binding/permease protein MsbA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 610 transmembrane" amino acids 40 to 61 (22 residues), see Phobius details amino acids 84 to 106 (23 residues), see Phobius details amino acids 160 to 179 (20 residues), see Phobius details amino acids 185 to 204 (20 residues), see Phobius details amino acids 271 to 292 (22 residues), see Phobius details amino acids 297 to 323 (27 residues), see Phobius details PF00664: ABC_membrane" amino acids 42 to 300 (259 residues), 49 bits, see alignment E=6.8e-17 PF00005: ABC_tran" amino acids 380 to 532 (153 residues), 113.1 bits, see alignment E=1.7e-36

Best Hits

Swiss-Prot: 52% identical to Y1051_HAEIN: Uncharacterized ABC transporter ATP-binding protein HI_1051 (HI_1051) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: None (inferred from 92% identity to pba:PSEBR_a1402)

Predicted SEED Role

"Lipid A export ATP-binding/permease protein MsbA" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QUC0 at UniProt or InterPro

Protein Sequence (610 amino acids)

>PfGW456L13_4461 Lipid A export ATP-binding/permease protein MsbA (Pseudomonas fluorescens GW456-L13)
MLYRRFEKLIDVFREAPTASPPDRVFPFYTYYLKQVWPSFAALLIVGLIGALIEVALFSY
LSRIIDLAQGTPNINLFQDHALELTWMVVVALVLRPIFVGLHDLLVHQTLSPSMTSMIRW
QNHSYVLKQSLNFFQNDFAGRIAQRIMQTGNSLRDSAVQAVDALWHVLIYAISSLVLFAE
ADWRLMIPLLTWIFAFIGALCYFVPRVKDRSVVASDARSKLMGRIVDGYTNITTLKLFAH
TNFEQQYAREAIKEQTEKAQLAGRVVTSMDVVITSMNGLLIVCTTGLALWLWTQSLISVG
AIALATGLVIRIVNMSGWIMWVVTGIFENIGMVQDGLQTISQPVSVTDRDQAKPLAVARG
EVRFEQVDFHYGKQSGIIGDLNLSIKAGEKIGLIGPSGAGKSTLVNLLLRLYDVEGGRIL
IDGQNIADVSQESLRERIGMITQDTSLLHRSIRDNLLYGKPDATDAQLWEAVHKARADGF
IPSLSDAEGRTGFDAHVGERGVKLSGGQRQRIAIARVLLKDAPILIMDEATSALDSEVEA
AIQESLETLMQGKTVIAIAHRLSTIARMDRLVVLENGKIAETGTHAELLAHGGLYARLWQ
HQTGGFVGID