Protein Info for PfGW456L13_446 in Pseudomonas fluorescens GW456-L13

Annotation: Cystine ABC transporter, ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 251 PF00005: ABC_tran" amino acids 17 to 171 (155 residues), 126.5 bits, see alignment E=1.2e-40

Best Hits

Swiss-Prot: 76% identical to YECC_ECOLI: L-cystine transport system ATP-binding protein YecC (yecC) from Escherichia coli (strain K12)

KEGG orthology group: K10010, cystine transport system ATP-binding protein [EC: 3.6.3.-] (inferred from 95% identity to pfo:Pfl01_0242)

MetaCyc: 76% identical to cystine ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"Cystine ABC transporter, ATP-binding protein"

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.- or 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QJG5 at UniProt or InterPro

Protein Sequence (251 amino acids)

>PfGW456L13_446 Cystine ABC transporter, ATP-binding protein (Pseudomonas fluorescens GW456-L13)
MIVVEKLTKQFKGQIVLNGIDLEVKEGEVVAIIGPSGSGKTTFLRCLNFLEEPTSGRIKV
GDIEVDTSRPLNQQQSLVRRLRQHVGFVFQNFNLFPHRTALENVIEGPIVVKKTPHADAV
ALGKKLLAKVGLAGKEDAYPRRLSGGQQQRVAIARALAMEPEVILFDEPTSALDPELVGE
VLATIRGLAEEKRTMVIVTHEMGFARDVANRVVFFDKGVIVEQGEAKALFANPKEERTKQ
FLSKFLNNAHN