Protein Info for PfGW456L13_4422 in Pseudomonas fluorescens GW456-L13

Annotation: Transcriptional regulator SlyA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 144 PF12802: MarR_2" amino acids 32 to 91 (60 residues), 52.2 bits, see alignment E=8.3e-18 PF01047: MarR" amino acids 33 to 91 (59 residues), 40.5 bits, see alignment E=3.1e-14 PF09339: HTH_IclR" amino acids 40 to 83 (44 residues), 24.3 bits, see alignment E=3.3e-09

Best Hits

Swiss-Prot: 38% identical to SLYA_BLOPB: Transcriptional regulator SlyA (slyA) from Blochmannia pennsylvanicus (strain BPEN)

KEGG orthology group: K06075, MarR family transcriptional regulator, transcriptional regulator for hemolysin (inferred from 95% identity to pfo:Pfl01_1469)

Predicted SEED Role

"Transcriptional regulator SlyA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A0F4U1E0 at UniProt or InterPro

Protein Sequence (144 amino acids)

>PfGW456L13_4422 Transcriptional regulator SlyA (Pseudomonas fluorescens GW456-L13)
MPLTDQHRFGMQLAQMSRGWRAELDRRLAGMGLSQARWLVLLHLARFEEAPTQRELAQSV
GVEGPTLARLLDSLESQGLVQRQAVLEDRRAKKIVLCAPARPLIEQIETIATQLRHELFE
GVDEADLKVCMRVHGHILGNLEKS