Protein Info for PfGW456L13_4400 in Pseudomonas fluorescens GW456-L13

Annotation: Aromatic amino acid transport protein AroP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 473 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 47 to 66 (20 residues), see Phobius details amino acids 86 to 106 (21 residues), see Phobius details amino acids 125 to 144 (20 residues), see Phobius details amino acids 154 to 175 (22 residues), see Phobius details amino acids 196 to 220 (25 residues), see Phobius details amino acids 241 to 261 (21 residues), see Phobius details amino acids 286 to 309 (24 residues), see Phobius details amino acids 343 to 364 (22 residues), see Phobius details amino acids 370 to 389 (20 residues), see Phobius details amino acids 409 to 432 (24 residues), see Phobius details amino acids 438 to 455 (18 residues), see Phobius details PF00324: AA_permease" amino acids 19 to 463 (445 residues), 424.1 bits, see alignment E=7.1e-131 PF13520: AA_permease_2" amino acids 23 to 450 (428 residues), 120.2 bits, see alignment E=1.1e-38

Best Hits

Swiss-Prot: 67% identical to AROP_SALTS: Aromatic amino acid transport protein AroP (aroP) from Salmonella typhimurium (strain SL1344)

KEGG orthology group: K03293, amino acid transporter, AAT family (inferred from 94% identity to pba:PSEBR_a4351)

Predicted SEED Role

"Aromatic amino acid transport protein AroP" in subsystem Aromatic amino acid degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QV97 at UniProt or InterPro

Protein Sequence (473 amino acids)

>PfGW456L13_4400 Aromatic amino acid transport protein AroP (Pseudomonas fluorescens GW456-L13)
MSGQNPQSGELKRGLKNRHIQLIALGGAIGTGLFLGSAGVLKSAGPSMILGYAICGFIAF
MIMRQLGEMIVEDPVAGSFSHFAHKYWGGFAGFLSGWNCWILYILVGMSELTAVGKYIHY
WAPDIPTWASAAAFFVLINAINLANVKVFGEAEFWFAIIKVVAIVGMIALGSYLLVSGNG
GPQAAVSNLWSHGGFFPNGVTGLVMAMAFIMFSFGGLEMLGFTAAEADKPKTVIPKAINQ
VIYRILIFYIGALVILLSLTPWDSLLTTLNASGDSYSGSPFVQVFSMLGSNTAAHILNFV
VLTAALSVYNSGTYCNSRMLLGMAEQGDAPKALAKIDKRGVPVRSILASAAVTLIAVLLN
YLIPHSALELLMSLVVATLVINWAMISYSHFKFRQHMNKTKQTPLFKALWYPYGNYICLA
FVLFILGVMLLIPGIQTSVYAIPVWLVFMWVCYGIKNKRSAQHALQVAGSAAK