Protein Info for PfGW456L13_4373 in Pseudomonas fluorescens GW456-L13

Annotation: Cephalosporin hydroxylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 242 PF04989: RMNT_CmcI" amino acids 39 to 241 (203 residues), 326.1 bits, see alignment E=9.6e-102 PF13578: Methyltransf_24" amino acids 74 to 180 (107 residues), 46.8 bits, see alignment E=5.1e-16

Best Hits

KEGG orthology group: None (inferred from 92% identity to pfo:Pfl01_1516)

Predicted SEED Role

"Cephalosporin hydroxylase" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QQ63 at UniProt or InterPro

Protein Sequence (242 amino acids)

>PfGW456L13_4373 Cephalosporin hydroxylase (Pseudomonas fluorescens GW456-L13)
MNPHEQFREEVKENIEGLQQDKALQATSLDWVGTTAKHKYTYNFSWMGRPIIQFPQDMVA
MQEIIWALRPDIIVETGIAHGGSLVFYASMLELIGHGEVLGVDIDIRQHNREAIEAHPMS
KRIQMIQGSSIDPAIVEQVRQRVEGKKVLVVLDSNHTHEHVLEELRAYAPMTSVGSYCVV
MDTVVEDMPEDAFPDRPWGKGDNPKTAVWAYLEENDGFEIDQAIHSKLLITVAPDGYLRR
VR