Protein Info for PfGW456L13_4278 in Pseudomonas fluorescens GW456-L13
Annotation: Glycine betaine/L-proline ABC transporter, glycine betaine/L-proline- binding/permease protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K02002, glycine betaine/proline transport system substrate-binding protein (inferred from 90% identity to pfo:Pfl01_1606)Predicted SEED Role
"Glycine betaine/L-proline ABC transporter, glycine betaine/L-proline- binding/permease protein" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A293Q4W9 at UniProt or InterPro
Protein Sequence (283 amino acids)
>PfGW456L13_4278 Glycine betaine/L-proline ABC transporter, glycine betaine/L-proline- binding/permease protein (Pseudomonas fluorescens GW456-L13) MKMRRLLGAGAALVLAISSAVASAAGKDVTLGYVDGWSDSVATTNVAAEVIRQKLGYDVK LQAVATGIMWQGVATGKLDAMLSAWLPVTHGEYWTKNKDQVVDYGPNFKDAKIGLIVPEY VKAKSIDDLKTDDTFKNRIVGIDAGSGVMLKTDQAIKDYDLTGYQLKASSGAGMIAELTR AEKKNESIAVTGWVPHWMFAKWKLRFLEDPKGVYGAAETVNSIGSKGLEAKAPEVAKFLK NFQWESKDEIGQVMLAIQDGAKPEAAAKDWIAKHPERVADWTK