Protein Info for PfGW456L13_4221 in Pseudomonas fluorescens GW456-L13

Annotation: Permeases of the major facilitator superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 396 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 42 to 64 (23 residues), see Phobius details amino acids 76 to 94 (19 residues), see Phobius details amino acids 105 to 123 (19 residues), see Phobius details amino acids 135 to 156 (22 residues), see Phobius details amino acids 162 to 179 (18 residues), see Phobius details amino acids 212 to 231 (20 residues), see Phobius details amino acids 244 to 263 (20 residues), see Phobius details amino acids 272 to 292 (21 residues), see Phobius details amino acids 298 to 320 (23 residues), see Phobius details amino acids 334 to 354 (21 residues), see Phobius details amino acids 367 to 384 (18 residues), see Phobius details PF07690: MFS_1" amino acids 16 to 344 (329 residues), 62.7 bits, see alignment E=3e-21 PF00083: Sugar_tr" amino acids 36 to 120 (85 residues), 34.4 bits, see alignment E=1.2e-12

Best Hits

KEGG orthology group: None (inferred from 82% identity to pfo:Pfl01_1662)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QPT3 at UniProt or InterPro

Protein Sequence (396 amino acids)

>PfGW456L13_4221 Permeases of the major facilitator superfamily (Pseudomonas fluorescens GW456-L13)
MPGSHSNRASLWFLAVTLLSFLAASTAPTPLYHLYQEQMQFSAATLTLIFGVYALSLLAA
LLTVGSLSDYLGRKPVIFTAVMLNILAMLLFIHAESVAWLISARVLQGFATGMATAVLSA
TLLDTDREQGPLVNSVAPLLGMALGALGCGVLAEFAPAPLHLTFWLLLALFAMQAVYVWR
LRESVSRQPGVWASLRPTLHVPAQARSTLWRVLPLNTAVWALGGFYASLAPSLVRTATGS
TSNLIGGATVAALTVTGALMIYTLRNQAVTKALQLGACSLPAGVALILLGVHSASLPLFF
LGTLVAGCGFGAGFLGAVRSLVPQALPHERAGLMSAYYALSYLAFCLPALLAGNLERTFG
LVATTDGYGAMLIVLALSAMASLLRSRSARVCEANR