Protein Info for PfGW456L13_4126 in Pseudomonas fluorescens GW456-L13

Annotation: Hydantoin permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 513 transmembrane" amino acids 74 to 103 (30 residues), see Phobius details amino acids 135 to 160 (26 residues), see Phobius details amino acids 176 to 199 (24 residues), see Phobius details amino acids 209 to 227 (19 residues), see Phobius details amino acids 247 to 269 (23 residues), see Phobius details amino acids 288 to 310 (23 residues), see Phobius details amino acids 330 to 359 (30 residues), see Phobius details amino acids 371 to 389 (19 residues), see Phobius details amino acids 395 to 419 (25 residues), see Phobius details amino acids 449 to 469 (21 residues), see Phobius details amino acids 475 to 492 (18 residues), see Phobius details PF02133: Transp_cyt_pur" amino acids 47 to 480 (434 residues), 278.4 bits, see alignment E=5.3e-87

Best Hits

KEGG orthology group: K03457, nucleobase:cation symporter-1, NCS1 family (inferred from 94% identity to pfo:Pfl01_1756)

Predicted SEED Role

"Hydantoin permease" in subsystem Hydantoin metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293Q4I2 at UniProt or InterPro

Protein Sequence (513 amino acids)

>PfGW456L13_4126 Hydantoin permease (Pseudomonas fluorescens GW456-L13)
MRTSLSNNNIALDLPSSHSIHTVDNQAHHAPVVLSPRLHNKDLAPTKSEGRRWGRYSIFA
LWTNDVHNIANYSFAIGLYALGLGGWQILLSLGIGAALVYFFMNLSGYMGQKTGVPFPVI
SRISFGIHGAQIPALIRAVIAIAWFGIQTYLASVVFRVLLTAVHPGFADYDHDSILGLST
LGWVCFVAIWFVQLAILAYGMEMVRRYEAFAGPVILLTVAALAAWMYTQADATIAWSIRE
PLTGGEMWRNIFAGGALWLAIYGTLILNFCDFARSSPCRKTIKVGNFWGLPVNILVFAGI
TVLLCGAQFQINGRIIESPTEIIASIPNTFFLVLGCLAFLIVTVAVNIMANFVAPAFVLS
NLAPKYLTFRRAGLISATIAVLILPWNLYNSPLVIVYFLSGLGALLGPLYGVIMVDYWLV
RKGRINVPQLYSEDPDGAYYYSRGVNLRAVAAFIPAALIAIVLALVPGFHSVSPFSWLIG
AGIAGMLYLIIAKRQPHYVDVSGEAIAVDNVSH