Protein Info for PfGW456L13_403 in Pseudomonas fluorescens GW456-L13

Annotation: 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00459: Inositol_P
  • amino acids 8 to 262 (255 residues), 174.2 bits, E=2e-55
• TIGR01331: 3'(2'),5'-bisphosphate nucleotidase
  • amino acids 9 to 258 (250 residues), 282.8 bits, E=1.3e-88

Best Hits

Swiss-Prot: 52% identical to CYSQ_ECOL6: 3'(2'),5'-bisphosphate nucleotidase CysQ (cysQ) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K03677, CysQ protein (inferred from 90% identity to pfo:Pfl01_0285)

MetaCyc: 51% identical to 3'(2'),5'-bisphosphate nucleotidase (Escherichia coli K-12 substr. MG1655)
3'(2'),5'-bisphosphate nucleotidase. [EC: 3.1.3.7]

Predicted SEED Role

"3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7)" (EC 3.1.3.7)

KEGG Metabolic Maps

• Sulfur metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.7

Sequence Analysis Tools

See A0A293QIZ6 at UniProt or InterPro

Protein Sequence (275 amino acids)

>PfGW456L13_403 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) (Pseudomonas fluorescens GW456-L13)
MNFPHPLMAPVIELALQAGEAILPFWRTGTAVTAKADDSPVTAADLAAHHLILAGLTALD
PSIPVLSEEDANIPQDVRAGWQRWWLVDPLDGTKEFISGSEEFTVNIALIENGRVVFGVV
SMPTNGRFYVGGAGLGAWRGDKGGTPVAIKVRDALAPGESFTVVASRRHSSPEQERLLAG
LSASLGELQLANIGSSLKFCLLAEGAADCYPRLAPTSQWDTAAAQGVLEGAGGEVLELSG
EPFSYPARASLLNAFFLALPAKAAWREKLLELARS