Protein Info for PfGW456L13_4019 in Pseudomonas fluorescens GW456-L13

Annotation: Lipoprotein releasing system transmembrane protein LolE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 414 transmembrane" amino acids 21 to 48 (28 residues), see Phobius details amino acids 271 to 295 (25 residues), see Phobius details amino acids 315 to 343 (29 residues), see Phobius details amino acids 380 to 400 (21 residues), see Phobius details TIGR02212: lipoprotein releasing system, transmembrane protein, LolC/E family" amino acids 4 to 413 (410 residues), 496.5 bits, see alignment E=3e-153 PF12704: MacB_PCD" amino acids 27 to 242 (216 residues), 70.2 bits, see alignment E=3e-23 PF02687: FtsX" amino acids 274 to 407 (134 residues), 65.9 bits, see alignment E=3.5e-22

Best Hits

Swiss-Prot: 44% identical to LOLC_XYLFA: Lipoprotein-releasing system transmembrane protein LolC (lolC) from Xylella fastidiosa (strain 9a5c)

KEGG orthology group: K09808, lipoprotein-releasing system permease protein (inferred from 93% identity to pba:PSEBR_a1768)

Predicted SEED Role

"Lipoprotein releasing system transmembrane protein LolE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QP82 at UniProt or InterPro

Protein Sequence (414 amino acids)

>PfGW456L13_4019 Lipoprotein releasing system transmembrane protein LolE (Pseudomonas fluorescens GW456-L13)
MFRPLSIFIGTRYTRAKRRNRFVSFISMTSMIGLALGVLAMIVVLSVMNGFQREMSSRIL
GMVPHATIVGVNPIDDWKPVAAAAMKNPEVTAAVPFTEMEGMLSYKGTMQPIQVSGVDPA
LEGQVSIVAKHIVQGSLEALKPGEFGVVIGQITARRFRLNVGDKITLIVPEVSNAPGGIT
PRMQRLNVVGVFKVGAELDGTMALIHMADAAQMQRWEPNQVQSVRLAVKDLYAAPQVSND
IATGLGAAYKADDWTHTQGSLFSAMKMEKTMIGLLLLMIVAVAAFNIIATLIMVVNDKGA
DIAILRTIGATPRQIMAIFVVQGTVIGIVGTLIGGVLGVIAALNVSQIVGWIERVSGQHI
FSSDVYFVSNLPSELQGADVALICTAGFVMSFLATVYPAWRAAKIEPAHALRYS