Protein Info for PfGW456L13_4009 in Pseudomonas fluorescens GW456-L13

Annotation: Transaldolase (EC 2.2.1.2)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 transmembrane" amino acids 154 to 168 (15 residues), see Phobius details TIGR00874: transaldolase" amino acids 4 to 308 (305 residues), 458.5 bits, see alignment E=6.6e-142 PF00923: TAL_FSA" amino acids 14 to 303 (290 residues), 318.3 bits, see alignment E=2.4e-99

Best Hits

Swiss-Prot: 97% identical to TAL_PSEPF: Transaldolase (tal) from Pseudomonas fluorescens (strain Pf0-1)

KEGG orthology group: K00616, transaldolase [EC: 2.2.1.2] (inferred from 97% identity to pfo:Pfl01_3847)

MetaCyc: 60% identical to transaldolase B (Escherichia coli K-12 substr. MG1655)
Transaldolase. [EC: 2.2.1.2]

Predicted SEED Role

"Transaldolase (EC 2.2.1.2)" in subsystem Folate Biosynthesis or Fructose utilization or Pentose phosphate pathway (EC 2.2.1.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.2.1.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QP74 at UniProt or InterPro

Protein Sequence (308 amino acids)

>PfGW456L13_4009 Transaldolase (EC 2.2.1.2) (Pseudomonas fluorescens GW456-L13)
MTSKLEQLKQMTTVVADTGDFEAIARVKPVDATTNPSLLLKAAAIPAYAELLNACVNDCK
GDVGLASDRFGVAVGQEILKVIPGRISTEVDARLSFDTDAMLKRAHRLIELYDKAGIGRD
RVLIKIASTWEGIRAAEILEKEGIQTNLTLLFSFAQAAACADAGVFLISPFVGRIYDWYK
KANGNDYTGADDPGVQSVTRIYNYYKANDYKTVVMGASFRNLGQIEQLAGCDRLTISPDL
IDKLAADTGKLERKLAPGHAGEARLSLNESQFRWLSNEDAMATEKLAEGIRQFARDQEKL
EALLQAKL