Protein Info for PfGW456L13_3883 in Pseudomonas fluorescens GW456-L13

Annotation: Cyclic di-GMP binding protein precursor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 752 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details transmembrane" amino acids 720 to 742 (23 residues), see Phobius details PF03170: BcsB" amino acids 44 to 655 (612 residues), 740.4 bits, see alignment E=7.7e-227

Best Hits

Swiss-Prot: 61% identical to BCSB_PSEFS: Cyclic di-GMP-binding protein (bcsB) from Pseudomonas fluorescens (strain SBW25)

KEGG orthology group: None (inferred from 61% identity to pfs:PFLU0302)

Predicted SEED Role

"Cyclic di-GMP binding protein precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QTA0 at UniProt or InterPro

Protein Sequence (752 amino acids)

>PfGW456L13_3883 Cyclic di-GMP binding protein precursor (Pseudomonas fluorescens GW456-L13)
MLIACSLVGWNGWALSAAAQISATEPAVLPVASLPVTDAPGNSYTRTLKELGKSYSMTLK
GVEATDSVNFDVRADEVVTAAQVTLQYSYSPALLADLSQINVLINDQVAASLPLPKEEAG
KLQTRTVQIPPQTITEFNRLSLQFIGHYTMQCEDPLHSSLWARIGNESQLSLQVTSIKQP
NDLSALPLPLFDRRDASPLKLPFVFAARPGGPELEAAGILSSWFGALASYRGATFPASLT
SLPAKGNAVVFVIGNESTTLSGLPIKEATGPTLTLMSNPNDAQGKLLIVSGRDGADLKVA
ATALVLGGSAFSGQSVVIDRIDSLKPRQPYDAPNWLPSDRPVRLGELAKPAELNVSGYNP
GQMTVALRLPPDLFNWREPGAQLDLKYRYTPQPVSTNSSLLISFNDTFIKSIDLPSIEKL
GNSDSLLSMLKTDDSLARTSRMLLPLNSVALQSRLQFRFMYDYIKQGECRDIIIDNMRGV
IDPDSTLDLSQYEHFMAMPNLGVFKDSGFPFTRMADLSETSVILPDEPGPADLSAYLTLL
GRFGDSTGYPATGVKVVHADQVAEQSDRDLLVLASGNNQPLLQQWQSLLPAKGEDAAQYF
ELSDLPLRLRNWISPDTKTNLREARSSFRFSAEDGSAYLTGFESPLKSGRSVVFIAGTRP
DGLADVTNALLSSEENAQQLQGSLVVVRGKHVESLVAEQDYYVGRLGPLRYLQWYLSQNV
IALMLFTLLGVLLLACMAYLALRLRAKRRLGQ