Protein Info for PfGW456L13_3638 in Pseudomonas fluorescens GW456-L13

Annotation: Multidrug resistance ABC transporter ATP-binding and permease protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 572 transmembrane" amino acids 35 to 55 (21 residues), see Phobius details amino acids 107 to 130 (24 residues), see Phobius details amino acids 136 to 155 (20 residues), see Phobius details amino acids 222 to 242 (21 residues), see Phobius details amino acids 249 to 267 (19 residues), see Phobius details PF00664: ABC_membrane" amino acids 11 to 259 (249 residues), 71.7 bits, see alignment E=1.3e-23 PF00005: ABC_tran" amino acids 329 to 483 (155 residues), 121.1 bits, see alignment E=8.5e-39 PF01926: MMR_HSR1" amino acids 341 to 389 (49 residues), 22 bits, see alignment 2.2e-08

Best Hits

Swiss-Prot: 60% identical to Y1051_HAEIN: Uncharacterized ABC transporter ATP-binding protein HI_1051 (HI_1051) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: None (inferred from 93% identity to pba:PSEBR_a2556)

Predicted SEED Role

"Multidrug resistance ABC transporter ATP-binding and permease protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QSJ1 at UniProt or InterPro

Protein Sequence (572 amino acids)

>PfGW456L13_3638 Multidrug resistance ABC transporter ATP-binding and permease protein (Pseudomonas fluorescens GW456-L13)
VSIYEAWLFSFLGQVVDLLSTWQAGGEAAAQESRVLWGMGIVMVTSVGLVALRTMVQHQI
LAINLPLRLRWDFHRLMLRQSLSFFSDEFSGRVTTKVMQTALAVRDVLFTLIEIVPGIGV
YFIAIIALAGGFALKLMLPFVAWVVLFGLAMLYFVPRLGKVGQEQANARSMMTGRISDAY
TNITTVKLFSHSNREAHFARAAMEDFKHTGFRQMRLVSQFEIVNQALVVALIMAAGGYAL
WLWHQGEVGAGAVAAITAMALRINGMSNWIMWQMTSLFESIGTVQDGMATLTQGTKVQDT
PGAGVLVTSGGAVTFDKVSFNYNGERQVLDGLSLSIRPGEKIGLVGRSGAGKSTLINLLL
RFYDVDSGEIRIDGQNIAQVTQDSLRGCIGMVTQDTSLLHRSIRDNIAYGRPDATDAQIR
SAAASAQADEFISQLSDRQGHTGYDTLVGERGIKLSGGQRQRVAIARVMLKNAPILLLDE
ATSALDSEVEVAIQESLDEMMQGKTVIAIAHRLSTIAAMDRLIVMDDGRIIEQGTHTELL
GKNGVYARLWQHQSGGFLGEDKGVVEEAMDQA