Protein Info for PfGW456L13_3633 in Pseudomonas fluorescens GW456-L13

Annotation: Transcriptional activator MetR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 346 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF00126: HTH_1" amino acids 48 to 106 (59 residues), 54.8 bits, see alignment E=7.4e-19 PF03466: LysR_substrate" amino acids 138 to 333 (196 residues), 126.6 bits, see alignment E=9.1e-41

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QN46 at UniProt or InterPro

Protein Sequence (346 amino acids)

>PfGW456L13_3633 Transcriptional activator MetR (Pseudomonas fluorescens GW456-L13)
VKGRVVIVVGLRWLCWIQIASAPNTSHAHNFTQFCELFSGRITMRLTLDHLVMLQTLSEV
DSITAVAERLWLTPSAVSHRIREAERRLGVSLTERSGGKLRLSPAGVRLERAAKDIIAIL
NEAESEARSMAGGVTAFVRMGVTSYGPFRWIPKFIKHYSSLRPDIEITLVTVPRNDVYAS
LMQGRLDVSIIDDGMVPSGVAKLPLFRDDLIAIMATDHPLAGRKNIYAEDFKTYNLVTYS
TDRASGWEYDRFFAPASILPRRMITVELIEAIVELVRSGYGISILQRDLVTPSLERGELA
WAALNDGLDIAWNAIVRPSEREDSEVSKMVTELDTWIKNAGKPERS