Protein Info for PfGW456L13_3574 in Pseudomonas fluorescens GW456-L13

Annotation: Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 310 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF01965: DJ-1_PfpI" amino acids 42 to 167 (126 residues), 56.7 bits, see alignment E=4.2e-19 PF00165: HTH_AraC" amino acids 216 to 252 (37 residues), 34.8 bits, see alignment 2e-12 PF12833: HTH_18" amino acids 228 to 306 (79 residues), 72.5 bits, see alignment E=4.2e-24

Best Hits

KEGG orthology group: None (inferred from 66% identity to reh:H16_B1789)

Predicted SEED Role

"Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QSC9 at UniProt or InterPro

Protein Sequence (310 amino acids)

>PfGW456L13_3574 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain (Pseudomonas fluorescens GW456-L13)
MHQIGLIVYPGFQVLGLAMCAAFELANSAGDEPLYRIALLSEPGGLVQTSAGFAVQTEAF
DQRAFDTLLVLGDNLIRPTTPGMLEFLRRASHGTRRLGSICTGAIALAQAGLLDGRRATT
HWAHVSAFRKAYPNVKVEEDRIFINDGNVWTAAGMSACVDLALALVENDLGIDVARKVAR
QLVVYHRRSGGQSQFSVMLELAPKTDRIQAALNYARQNLKSALSVEELASAANLSPRQFS
RVFHAETGQSPAKAIENLRVESARLMMETGRHSIDAVATDTGFGDRERMRRAFIRAFGQP
PQVIQRASRG