Protein Info for PfGW456L13_3456 in Pseudomonas fluorescens GW456-L13

Annotation: Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1187 transmembrane" amino acids 723 to 747 (25 residues), see Phobius details PF02775: TPP_enzyme_C" amino acids 457 to 545 (89 residues), 26.3 bits, see alignment 9e-10 PF01558: POR" amino acids 730 to 930 (201 residues), 73.3 bits, see alignment E=4.2e-24 PF20169: DUF6537" amino acids 959 to 1158 (200 residues), 219 bits, see alignment E=9.2e-69

Best Hits

Predicted SEED Role

"Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits" in subsystem Aromatic amino acid interconversions with aryl acids

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QSL6 at UniProt or InterPro

Protein Sequence (1187 amino acids)

>PfGW456L13_3456 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits (Pseudomonas fluorescens GW456-L13)
MSASPSLDDKYIQHSGKVLLTGIQALVRLPLMQRQRDLANGLNTAGFISGYRGSPLGGFD
QALWKARDYLKEHHTVFHPGMNEDLAATSIWGTQQVNIFEGATYDGVFGMWYGKGPGVDR
CGDVFRHANAAGTSQFGGVLAIAGDDHGARSSSLPHQTEHIFKAVMMPVLAPSGVQEYLD
YGMHGWAMSRYSGCWVALKAVADTVESAAVVDIDIHRVQPIIPDIPLPEGGLNIRWPDPP
LAQEQRLLEHKLYAALAYARVNRLDRIVMDSPKARIGIITSGKSYLDVCQALKILGIDET
LAQQIGLRVYKVGMVWPLEAEGVRQFAEGLEEIVVVEEKRHMIEYQLKEELYNWREDVRP
RIVGKFDDKGEWSLPHTGWLLPATNDLTPAMIARALAKRILHLHQNGPLQVSLAVLDAQL
ASKGQFSNLMERVPHYCSGCPHNTSTKVPQGSRALAGIGCHYMAAWIYPQTQTFSQMGGE
GVAWIGQAPFTKTRHVFANLGDGTYFHSGILAIRAAIAAKVQITYKILYNDAVAMTGGQP
VDGSLSVAQISRQLAAEGVQRIVVVSDDVEKYQHIRDLADGVPVLRRDKMDEVQEQLRQF
QGVSAIIYDQTCAAEKRRRRKRGKFPDPARRVVINEAVCEGCGDCSSKSNCMSVVAVETE
YGRKREIDQSSCNKDFTCLNGFCPSFVTVEGGTLRKPKALASAKNDVWDLPTPATVALEE
PYSILVTGVGGTGVVTIGALLGMAAFIEGKGTLNLDMAGMAQKGGAVWSHIRIAAHQEQL
FAPRIAEGETALLLGCDLVVSANTETLSKLRHGVTHALINSEETITSAFVRTFAQQAETG
DLLKHPDPTFQTGNMSEQIAEAVGTEHADFIDASKIATALMGDSIATNTFMLGYAYQKGW
LPVGKAALLQAIELNGTAVPFNLSAFDWGRRSAHDLPRVLRKLEAGKVQSPDRLLSQSLE
ETLARRMEFLTAYQNYAYAQRYRYRVEQFIKAETALLGQPGKLSASVARYYFKVLAIKDE
YEVARLFTDGQFLEKIQAGFEGDYRLRFHLAPPLLNDNGSGREPKKRSFGPWMLQGFKLL
ARLKFLRNTWLDPFGRTHERKVERNWLANYEQILDEVLAGLTTQKLGLAQDLVELPESVR
GYGPVKERFLGHAQQRQAQLLEQWRNGNTAQFHDASQSNSKIAVTQL