Protein Info for PfGW456L13_34 in Pseudomonas fluorescens GW456-L13

Annotation: Sensory box histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 895 PF08447: PAS_3" amino acids 426 to 508 (83 residues), 38.8 bits, see alignment E=1.4e-13 TIGR00229: PAS domain S-box protein" amino acids 524 to 649 (126 residues), 27.7 bits, see alignment E=1.2e-10 PF08448: PAS_4" amino acids 535 to 644 (110 residues), 32 bits, see alignment E=1.9e-11 PF02518: HATPase_c" amino acids 771 to 882 (112 residues), 75 bits, see alignment E=9.6e-25

Best Hits

KEGG orthology group: K00936, [EC: 2.7.3.-] (inferred from 75% identity to pfo:Pfl01_0637)

Predicted SEED Role

"Sensory box histidine kinase"

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QFK4 at UniProt or InterPro

Protein Sequence (895 amino acids)

>PfGW456L13_34 Sensory box histidine kinase (Pseudomonas fluorescens GW456-L13)
VHSFGLQMQLNAEGRVVQLSGPLRHLLAQHPPSEQAPHLFDFLLPHSSLVIEGSPADWQG
QTLDLDFYSLNGPPLHLRGWVQPLADTWLLQMLDIGDLLLERLQSRNREQCQVLAQQIAE
QLRLCSLTRLPEVLTEQLQSLAQRFQIPCIALALLDEQEHGWQIQQHYAAPDAPQLWQNG
QRLGTGLDSLSGSAPQHLTPREHPRLQGTFGNTDGFVVPYHDAQGVVAWLLCGFFTAQKR
APDVTERDWLQITAALASPLLGRLREHRHHLQLERLESLQALLGTGWWEVFSDSDEVQLA
PSLATTLNLGMSRLSMQDWLDQVYPADREELRICLQDLQETGTPLLLCVRLYRPYGAPAP
AWYRLQGQALGAGKNRRLVGFMLDISDIKNQEQSAIAAHARLDNLIASSPAVIYVQRYVD
GTLHPVFFSDSLLPLLGWTLADCAPGALGERVHPDDRLQYFERTRLLLREGSVRARYRLR
DSHGDYHWLLDEAKLLRNDLGLPVEAVGLWLDITEATLATEQVRQSEERYRMLVEDSPAM
ICRYQPDLTLTFGNRPLATCLELAPEQLPGVNLGDWMSGEQRTAFIQRLNRLSPEFPVST
AEINLQLPGREHAWWIWSDRGVFDEQGRLLEVQAVGRDNTEVRRAQQQLTQSAKMATLGE
MATGLAHEINQPLNVMRMAIVNVLKRLNNGDVQVDYLIDKLTRIDTQVQRAARVVDHMRV
FGRRSETEQQPFNPVQAIEGTLSLLSEDLRDKGVDLRISETGFEVQVRGYVDQLEQVLIN
LMVNARDALLGKRETLPGFKPWISLYTERDTHSVRLWVEDNGGGIDPRLLERIFEPFFTT
KPVGFGTGLGLSVSYDIVENMGGKLSVRNSTEGARFCIELPIVLPDQITRDGRPE