Protein Info for PfGW456L13_3370 in Pseudomonas fluorescens GW456-L13

Annotation: Agmatine deiminase (EC 3.5.3.12)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR03380: agmatine deiminase
  • amino acids 7 to 364 (358 residues), 542.4 bits, E=2.2e-167
• PF04371: PAD_porph
  • amino acids 15 to 362 (348 residues), 368.4 bits, E=1.7e-114

Best Hits

Swiss-Prot: 54% identical to AGUA1_LISMF: Putative agmatine deiminase 1 (aguA1) from Listeria monocytogenes serotype 4b (strain F2365)

KEGG orthology group: K10536, agmatine deiminase [EC: 3.5.3.12] (inferred from 96% identity to pfo:Pfl01_2154)

MetaCyc: 51% identical to agmatine deiminase subunit (Pseudomonas aeruginosa)
Agmatine deiminase. [EC: 3.5.3.12]

Predicted SEED Role

"Agmatine deiminase (EC 3.5.3.12)" in subsystem Arginine and Ornithine Degradation or Polyamine Metabolism (EC 3.5.3.12)

MetaCyc Pathways

• L-arginine degradation IV (arginine decarboxylase/agmatine deiminase pathway) (3/3 steps found)
• putrescine biosynthesis II (3/3 steps found)
• superpathway of polyamine biosynthesis II (6/8 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Urea cycle and metabolism of amino groups

Isozymes

Compare fitness of predicted isozymes for: 3.5.3.12

Use Curated BLAST to search for 3.5.3.12

Sequence Analysis Tools

See A0A293QMF8 at UniProt or InterPro

Protein Sequence (374 amino acids)

>PfGW456L13_3370 Agmatine deiminase (EC 3.5.3.12) (Pseudomonas fluorescens GW456-L13)
MARLLDTTPKQDGFRLPGEFEAKSGCWLGWPERTDVWRNGAKPAQKVWVQIVTAISMSEP
VTVCASAAQFATARRQLPPQVRVVEMTCNDTWFRDSGPCFVVNDQRGEVRGVDFEFNAYG
GLDGGLYYPWDKDDQIAGKILEIERFDRYRAPLIAELGGIQSDGQGSILTTEQCLLNRNR
NQHLGKDEVTRRLTDYLGAEQVIWLPRGCKFDETDGHVDDLACFVRPGEVVLQWTDNRDD
PQWEIYQEAYDILRSTRDSRGRELIVHKLPQPDVLEWTAEEAEGLDRQDSTHTRQAGTKI
CASYINYYAGNSSIVVPLFGDRNDKVALATLAELFPQHSIVGIENSREILLGGGNVACIT
MPQYAVTTSNKKGA