Protein Info for PfGW456L13_3364 in Pseudomonas fluorescens GW456-L13

Annotation: Permease of the drug/metabolite transporter (DMT) superfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 transmembrane" amino acids 20 to 40 (21 residues), see Phobius details amino acids 46 to 67 (22 residues), see Phobius details amino acids 78 to 99 (22 residues), see Phobius details amino acids 105 to 125 (21 residues), see Phobius details amino acids 132 to 150 (19 residues), see Phobius details amino acids 162 to 178 (17 residues), see Phobius details amino acids 190 to 209 (20 residues), see Phobius details amino acids 221 to 241 (21 residues), see Phobius details amino acids 248 to 270 (23 residues), see Phobius details amino acids 276 to 293 (18 residues), see Phobius details PF00892: EamA" amino acids 17 to 143 (127 residues), 52.8 bits, see alignment E=2.4e-18 amino acids 160 to 290 (131 residues), 52.1 bits, see alignment E=3.9e-18

Best Hits

Swiss-Prot: 71% identical to YDEK_BACSU: Uncharacterized transporter YdeK (ydeK) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 84% identity to pfl:PFL_2405)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QR94 at UniProt or InterPro

Protein Sequence (298 amino acids)

>PfGW456L13_3364 Permease of the drug/metabolite transporter (DMT) superfamily (Pseudomonas fluorescens GW456-L13)
MERTSNLQPRTLENSTSGWINGLIGVVIFSGSLPATRVAVLEFDPVFLTVARATIAAVLA
LCLLWLFKEKRPARQQLIPLMIVALGVVIGFPLLTALALQYVTSAHSIVFVGLLPLATAV
FGVLRGGERPRAAFWIFSVLGSLLVVGFALSQGLTASPQGDILMLLAILACGLGYAEGAK
LSRTLGGWQVISWALVLSLPVVAVLSWMRMPASFTGISTPAWFSLAYVSLFSMLIGFVFW
YRGLAQGGIAAVGQLQLLQPFFGLTLAATLLHEHVSLGMLGVTVAVILCVAGAKKFAK