Protein Info for PfGW456L13_3265 in Pseudomonas fluorescens GW456-L13

Annotation: Acriflavin resistance plasma membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1035 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 336 to 353 (18 residues), see Phobius details amino acids 361 to 381 (21 residues), see Phobius details amino acids 387 to 410 (24 residues), see Phobius details amino acids 431 to 454 (24 residues), see Phobius details amino acids 464 to 487 (24 residues), see Phobius details amino acids 529 to 548 (20 residues), see Phobius details amino acids 857 to 875 (19 residues), see Phobius details amino acids 882 to 902 (21 residues), see Phobius details amino acids 908 to 933 (26 residues), see Phobius details amino acids 955 to 974 (20 residues), see Phobius details amino acids 986 to 1012 (27 residues), see Phobius details PF00873: ACR_tran" amino acids 7 to 1012 (1006 residues), 1059.1 bits, see alignment E=0 PF03176: MMPL" amino acids 255 to 507 (253 residues), 32 bits, see alignment E=9.9e-12

Best Hits

Swiss-Prot: 56% identical to MDTC_CITK8: Multidrug resistance protein MdtC (mdtC) from Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)

KEGG orthology group: K07789, RND superfamily, multidrug transport protein MdtC (inferred from 69% identity to avn:Avin_28790)

Predicted SEED Role

"Acriflavin resistance plasma membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293Q209 at UniProt or InterPro

Protein Sequence (1035 amino acids)

>PfGW456L13_3265 Acriflavin resistance plasma membrane protein (Pseudomonas fluorescens GW456-L13)
MNLSGPFIKRPVATMLLSLAIMLLGGVSFGLLPVSPLPQMDFPVIVVQASLPGASPEVMA
STVATPLERSFGSIAGVNTMSSRSSQGSTRVILQFDLDRDINGAAREVQAAINASRTLLP
SGMRSMPTYKKVNPSQAPIMVLSLTSDVLEKGQLYDLASTILSQSLSQVQGVGEVQIGGS
SLPAVRIELEPQSLNQYGVALDDVRNTIANANVRRPKGSVEDDQRLWQVQANDQLEKAKD
YESLIIHYNGGAALRLKDVAKVSDGVEDRYNSGFFNDDAAVLLVINRQAGANIIETVNEI
KAQLPALQAVLPASVKLNLAMDRSPVIKATLHEAEMTLLIAVALVILVVFLFLGNFRASL
IPTLAVPVSLVGTFAVMYLYGFSLNNLSLMALILATGLVVDDAIVVLENISRHIDEGVRP
MRAAYLGAQEVGFTLLSMNVSLVAVFLSILFMGGIIESLFREFSITLAAAIVVSLVVSLT
LTPMLCARWLKPHTPGQENRLQRWSRRTNDWMVGKYATSLDWVLRHKRLTLLSLFVTIGV
NIALYVVVPKAFLPQQDTGQLIGFVRGDDGLSFSVMQPKMEIFRRAVLKDEAVESVAGFI
GGNNGTNNAFMLVRLKPIKERSISAQKVIERLRKEMPKVPGAQLMLMADQDLQFGGGREQ
TTSQYSYILQSGDLGALREWYPKVVTALRALPELTAIDAREGRGARQVTLIVDRNQAKRL
GVDMDMVTAVLNNAYSQRQISTIYDSLNQYQVVMEVNPKYAQDPITLTQVQVITADGARI
PLSTIAHYENSLENDRVSHEGQFASESIAFDMAEGVTVEQGGAAIERAIAKVGLPEDVIA
KMAGTANAFAATQKSQPWMILGALVAVYLVLGVLYESYIHPLTILSTLPSAGVGALLSIY
ALGGEFSLISLLGLFLLIGVVKKNAILMIDLALQLERNQGMAPLESIRSACLQRLRPILM
TTLAAILGALPLLLSRAEGAEMRQPLGLTIIGGLIFSQVLTLYTTPVVYLYLDNLRHRFN
KWRGVRTDVALETPL