Protein Info for PfGW456L13_3218 in Pseudomonas fluorescens GW456-L13

Annotation: 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 653 PF00724: Oxidored_FMN" amino acids 11 to 342 (332 residues), 195 bits, see alignment E=6.7e-61 PF03486: HI0933_like" amino acids 391 to 430 (40 residues), 25.6 bits, see alignment 1.6e-09 PF07992: Pyr_redox_2" amino acids 391 to 620 (230 residues), 51.9 bits, see alignment E=2.4e-17 PF00070: Pyr_redox" amino acids 391 to 473 (83 residues), 22.8 bits, see alignment E=3.3e-08 PF12831: FAD_oxidored" amino acids 392 to 428 (37 residues), 28.1 bits, see alignment 4e-10 PF13450: NAD_binding_8" amino acids 394 to 428 (35 residues), 27.5 bits, see alignment (E = 9.7e-10)

Best Hits

KEGG orthology group: None (inferred from 86% identity to pfl:PFL_2703)

Predicted SEED Role

"2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34)" (EC 1.3.1.34)

Isozymes

Compare fitness of predicted isozymes for: 1.3.1.34

Use Curated BLAST to search for 1.3.1.34

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QRY4 at UniProt or InterPro

Protein Sequence (653 amino acids)

>PfGW456L13_3218 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34) (Pseudomonas fluorescens GW456-L13)
MTTSTPAFAHLFEPLEIRGKRLKNRIMSSGHDTSMPTDNLVNEQLIAYHRARAEGGAGLI
VLQVAGVHDSARYTSHVLMATDDACIEGYRKLAQTCHAHGTLVLSQVFHPGREIMESSDG
LLAVAYSASSVPNERFRVMPRALDQAMIDEIVAGYAAAARRLHQAGIDGVEVVASHGYLP
AQFINPRVNRRTDGYNGELDQRLRFLREVIAAVRAATDQQFIIGLRISADERDPEGLTED
ESLAAVQSLQAQLDYVHIVAGTSASLGGAVHIVPPMAIEAAYLAKEAGTFKASLNIPLFV
TGRINQPQEAELILARGQADVCGMTRALICDPQMPNKTDTGRVEDVRACIACNQACIGHF
HKGLPISCIQHPETGRELIFGERRQAPQRKRIMIAGGGPAGMKAATVAAQRGHEVTLYEA
SSQLGGQVLLAQLLPRRSEFGGASTNLQREMELAGVRVVRNTRVDRALVEQEKPDMVIVA
TGAEPYWPPFERGGELQVVDAWQVLRDEVRIGRSVVVVDWRCDWIGPGIAERLVRAGHQV
QLAVNGTHCGENLPLYVRDQLAGELHKLGVPITPYARLYGCDDNTVYLQHTASGEPMLME
NIDTLVLCQGHQPVDTLGAELQGLVEFRRIGDCLAPRTAEEAIYEGLKVAWEL