Protein Info for PfGW456L13_3155 in Pseudomonas fluorescens GW456-L13

Annotation: L-Proline/Glycine betaine transporter ProP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 429 transmembrane" amino acids 41 to 63 (23 residues), see Phobius details amino acids 74 to 97 (24 residues), see Phobius details amino acids 103 to 127 (25 residues), see Phobius details amino acids 138 to 161 (24 residues), see Phobius details amino acids 173 to 192 (20 residues), see Phobius details amino acids 224 to 248 (25 residues), see Phobius details amino acids 262 to 284 (23 residues), see Phobius details amino acids 292 to 311 (20 residues), see Phobius details amino acids 317 to 342 (26 residues), see Phobius details amino acids 361 to 379 (19 residues), see Phobius details amino acids 386 to 405 (20 residues), see Phobius details PF00083: Sugar_tr" amino acids 3 to 218 (216 residues), 88.5 bits, see alignment E=4.8e-29 amino acids 231 to 416 (186 residues), 39.3 bits, see alignment E=4e-14 PF07690: MFS_1" amino acids 7 to 371 (365 residues), 105.6 bits, see alignment E=2.6e-34 amino acids 258 to 409 (152 residues), 40.8 bits, see alignment E=1.4e-14

Best Hits

KEGG orthology group: K03762, MFS transporter, MHS family, proline/betaine transporter (inferred from 95% identity to pfs:PFLU3383)

Predicted SEED Role

"L-Proline/Glycine betaine transporter ProP" in subsystem Proline, 4-hydroxyproline uptake and utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QRL3 at UniProt or InterPro

Protein Sequence (429 amino acids)

>PfGW456L13_3155 L-Proline/Glycine betaine transporter ProP (Pseudomonas fluorescens GW456-L13)
VIVAAGIGNFVEWFDFAVYGFLATTIAQQFFPSGDASAALLKTFAVFAVAFAFRPLGGIF
FGMLGDRIGRKRTLAMTILLMAGATTLIGLLPTYAAIGVMAPILLSLIRCAQGFSAGGEY
AGACAYLMEHAPSDKRAWYGSFIPVSTFSAFAAAAVVAYALEASLSAEAMGSWGWRLPFL
IAAPLGLVGLYLRWKLDETPAFQAVTQEHAVAHSPLKETLRNHGAAICCLGAFVSLTALS
FYMFTTYFATYLQVAGGLSRATALLVSLIALLFAAAICPLAGLYSDRVGRRVTVMTACAL
LIVVVYPSFLMASSGSFAASIVGVMLLAIGAVLCGVVTAALLSETFPTRTRYTASAITYN
MAYTLFGGTAPLVATWLISTTGSNLSPAFYLIAIALLALAGGLALPETSRISLHDVAAQE
KAEGVGASA