Protein Info for PfGW456L13_315 in Pseudomonas fluorescens GW456-L13

Annotation: L-proline glycine betaine binding ABC transporter protein ProX (TC 3.A.1.12.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 318 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details TIGR03414: choline ABC transporter, periplasmic binding protein" amino acids 27 to 316 (290 residues), 437 bits, see alignment E=1.6e-135 PF04069: OpuAC" amino acids 34 to 288 (255 residues), 191.8 bits, see alignment E=8.4e-61

Best Hits

KEGG orthology group: K02002, glycine betaine/proline transport system substrate-binding protein (inferred from 94% identity to pfo:Pfl01_0369)

Predicted SEED Role

"L-proline glycine betaine binding ABC transporter protein ProX (TC 3.A.1.12.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (TC 3.A.1.12.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QJ85 at UniProt or InterPro

Protein Sequence (318 amino acids)

>PfGW456L13_315 L-proline glycine betaine binding ABC transporter protein ProX (TC 3.A.1.12.1) (Pseudomonas fluorescens GW456-L13)
MTSTKGLFARCLSILCGTALLSTGALAADDASCKTVRMGVVNWTDVIATSGMADVLLNGL
GYESKQTSAVQQIIFAGIRDKRLDIFLGYWKPAMDKNIAPFLAANQVKVMDKPSLADAQA
TLAVPDYVAAAGLKTFSDIARFKDQLGGKIYGIEPGSGANTTIKTMIETNHFGLKDFKLI
ESGEAGMLAAVQRAVNRKEFVVFVGWTPHPMNINMKIAYLTGSEDVYGPNEGAATVSTVT
APDYAKRCPNVNRLLENLTFTAAQESQLMVPIMERQTAQDVAKKWLREHPEDLQRWLAGV
SSLDGKDGVATVQASLKN