Protein Info for PfGW456L13_3109 in Pseudomonas fluorescens GW456-L13

Annotation: Type I restriction-modification system, DNA-methyltransferase subunit M (EC 2.1.1.72)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 505 PF12161: HsdM_N" amino acids 7 to 113 (107 residues), 40 bits, see alignment E=9.3e-14 PF02384: N6_Mtase" amino acids 123 to 431 (309 residues), 222.7 bits, see alignment E=1.1e-69 PF01170: UPF0020" amino acids 154 to 281 (128 residues), 23.9 bits, see alignment E=4.5e-09

Best Hits

Predicted SEED Role

"Type I restriction-modification system, DNA-methyltransferase subunit M (EC 2.1.1.72)" in subsystem Restriction-Modification System (EC 2.1.1.72)

Isozymes

Compare fitness of predicted isozymes for: 2.1.1.72

Use Curated BLAST to search for 2.1.1.72

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QR44 at UniProt or InterPro

Protein Sequence (505 amino acids)

>PfGW456L13_3109 Type I restriction-modification system, DNA-methyltransferase subunit M (EC 2.1.1.72) (Pseudomonas fluorescens GW456-L13)
MNASTLIQKVWNFCHTLRDDGVGYGDYLEQLTYLLFLKMAHEYSQEPYLRDTQIPKAYDW
ANLRSKTGEPLEAHYLATLHKLGEQPGMLGAIFFKAQNKIQDPAKLSRLVQLIDAESWVG
MDTDAKGDLYEGLLQKNAEDTKSGAGQYFTPRALIQAMVACIRPQPLKSIADPACGTGGF
FLVANEWLSGTGDWMKQSAEWLDYEAPKLNAKQKAFLRDETFHGNEIVPNTRRLCLMNLF
LHNIGELVGEPSVDRSDALISEPKVRVDYVLANPPFGKKSSMTITNEEGEEDKNALTYQR
QDFWETTSNKQLNFLQHIVNMLKVDGKAAVVLPDNVLYEGGAGEKIRKKLIETCDVHTIL
RLPTGIFYAHGVKANVVFFDAKPKDGKIHTKGAWFYDLRTNQHFTLKTRPLKLEDLRDFV
TCYNPENRYERAETERFKYYSYEDLVARDKASLDLFWLKDDSLDNLDDLPPPDVLQLEII
DHLEAALMAFRDVAAGLPTSVTLSE