Protein Info for PfGW456L13_3078 in Pseudomonas fluorescens GW456-L13

Annotation: ABC-type protease exporter, ATP-binding component PrtD/AprD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 582 transmembrane" amino acids 21 to 44 (24 residues), see Phobius details amino acids 60 to 86 (27 residues), see Phobius details amino acids 129 to 150 (22 residues), see Phobius details amino acids 156 to 175 (20 residues), see Phobius details amino acids 252 to 282 (31 residues), see Phobius details TIGR01842: type I secretion system ATPase" amino acids 18 to 558 (541 residues), 780 bits, see alignment E=6.1e-239 PF00664: ABC_membrane" amino acids 26 to 283 (258 residues), 46.5 bits, see alignment E=4.2e-16 PF00005: ABC_tran" amino acids 350 to 495 (146 residues), 104.7 bits, see alignment E=6.5e-34

Best Hits

Swiss-Prot: 59% identical to APRD_PSEAE: Alkaline protease secretion ATP-binding protein AprD (aprD) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K12536, ATP-binding cassette, subfamily C, bacterial HasD (inferred from 91% identity to pfo:Pfl01_2680)

Predicted SEED Role

"ABC-type protease exporter, ATP-binding component PrtD/AprD" in subsystem Protein secretion by ABC-type exporters

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QP29 at UniProt or InterPro

Protein Sequence (582 amino acids)

>PfGW456L13_3078 ABC-type protease exporter, ATP-binding component PrtD/AprD (Pseudomonas fluorescens GW456-L13)
MKMAKAPATAPLIKALGDYKSILISVGCFTALINILMLAPSIYMLQVYDRVLSSQNETTL
VMLSLMIVGFFAFIGLLEAVRSFIVIRIGSQLERRFNLRVYRAAFERNLFKGEGNAGQAL
GDLTHIRQFVTGPALFAFFDAPWFPVYLLVIYLFNIWLGVFATAGALLLIALAWLNESMT
KKPLGEAAACSQQSSQLATSHLHNAETIQAMGMLGALRNRWFQVHSRFLGLQNQASDTGA
VISSLSKTLRLCLQSLVLGLGALLVIKGDMTAGMMIAGSILMGRVLSPIDQLIAVWKQWS
GAKLAYRRLDALLQAFPSGDEAMALPAPKGQITFEQVSAAPPGQRAATLHLVSFSLAAGE
VMGVLGASGSGKSTLARVLVGVWPTLGGTVRLDGADIHRWNRDDLGPYIGYLPQDIELFS
GSIAQNIARFREADPQRVVAAAQQAGVHELILRLPQGYDTVLGEDGSGLSGGQKQRVALA
RALYGQPRLVVLDEPNSNLDTVGEAALASAIAQMKAQGTSVILVTHRSCALAQADKLLVL
NDGRLQAFGSSQDVLKALSGAQQAQHEKTAQAPGGLSMSWQS