Protein Info for PfGW456L13_2681 in Pseudomonas fluorescens GW456-L13

Annotation: Cytosine/purine/uracil/thiamine/allantoin permease family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 462 transmembrane" amino acids 30 to 51 (22 residues), see Phobius details amino acids 57 to 78 (22 residues), see Phobius details amino acids 98 to 122 (25 residues), see Phobius details amino acids 135 to 157 (23 residues), see Phobius details amino acids 163 to 181 (19 residues), see Phobius details amino acids 194 to 214 (21 residues), see Phobius details amino acids 234 to 259 (26 residues), see Phobius details amino acids 268 to 290 (23 residues), see Phobius details amino acids 296 to 314 (19 residues), see Phobius details amino acids 326 to 347 (22 residues), see Phobius details amino acids 353 to 375 (23 residues), see Phobius details amino acids 396 to 414 (19 residues), see Phobius details amino acids 427 to 449 (23 residues), see Phobius details PF02133: Transp_cyt_pur" amino acids 17 to 438 (422 residues), 170.5 bits, see alignment E=2.8e-54

Best Hits

KEGG orthology group: K03457, nucleobase:cation symporter-1, NCS1 family (inferred from 78% identity to pag:PLES_54891)

Predicted SEED Role

"Cytosine/purine/uracil/thiamine/allantoin permease family protein" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QQQ1 at UniProt or InterPro

Protein Sequence (462 amino acids)

>PfGW456L13_2681 Cytosine/purine/uracil/thiamine/allantoin permease family protein (Pseudomonas fluorescens GW456-L13)
MSAQRSPLIETRSIDFIPEAERHGSLYSQFTLWLGANLQITAIVTGALAVVLGGDVFWSL
IGLLIGQVLGGAVVALHAAQGPKLGLPQMISSRVQFGVYGAAIPIVLVCLMYLGFSATGA
VLSGQAIAQLISVSDSTGILIFAACIAFLTIFGYRVIHLVGRVASVLGIIAFAYLFTRLM
TLNDIGLLLDNRHFGWSTFLLAVSLSASWQIAFGPYVADYSRYLPSKTSSWKTFAAVGLG
TVLGAQTSMVLGVFAAALAGANFRGHEVATIVGLGSSGVIASLLYLSIVFGKVTVSTLNA
YGSFMCIATIISGFRRRLEITARQRMLFVLLIVAASTALALLGQYSFLNSFKYFILFLLT
FFTPWSAINLVDYYFINKERYDIPALSDPAGRYGRWNVLGISVYVIGVLIQLPFVDTHFY
SGPMVAQLGGVDISWIVGLLVPGVIYYALAKPSMSGVVVERG