Protein Info for PfGW456L13_2653 in Pseudomonas fluorescens GW456-L13

Annotation: FIG065221: Holliday junction DNA helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 440 PF05496: RuvB_N" amino acids 17 to 142 (126 residues), 52.7 bits, see alignment E=1.3e-17 PF07728: AAA_5" amino acids 50 to 140 (91 residues), 28.9 bits, see alignment E=3e-10 PF00004: AAA" amino acids 50 to 158 (109 residues), 61.6 bits, see alignment E=3.3e-20 PF16193: AAA_assoc_2" amino acids 184 to 260 (77 residues), 74.7 bits, see alignment E=1.7e-24 PF12002: MgsA_C" amino acids 261 to 427 (167 residues), 212.9 bits, see alignment E=8.2e-67

Best Hits

Swiss-Prot: 63% identical to RARA_COXBU: Replication-associated recombination protein A (rarA) from Coxiella burnetii (strain RSA 493 / Nine Mile phase I)

KEGG orthology group: K07478, putative ATPase (inferred from 98% identity to pfo:Pfl01_3584)

Predicted SEED Role

"FIG065221: Holliday junction DNA helicase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QQG3 at UniProt or InterPro

Protein Sequence (440 amino acids)

>PfGW456L13_2653 FIG065221: Holliday junction DNA helicase (Pseudomonas fluorescens GW456-L13)
MDLFRSTPIAQPLAARLRAANLDEYVGQEHVLARGKPLREALEQGALHSMIFWGPPGVGK
TTLARLLAEVSDAHFETVSAVLAGVKEIRQAVEIAKQQAAQYGRRTILFVDEVHRFNKSQ
QDAFLPYVEDGTLIFIGATTENPSFELNNALLSRARVYVLKSLDEAALRKLVYRALTEER
GLGKRNLTLSDEGFQMLLSAADGDGRRLLNLLENASDLAEDNGEIGTDLLQSLLGDTRRR
FDKGGEAFYDQISALHKSVRGSNPDGALYWFARMIDGGCDPLYLARRVVRMASEDIGNAD
PRALSLCLAAWEVQERLGSPEGELAVAQAITYLACAPKSNAVYMGFKTALRAAAEHGSLE
VPLHLRNAPTKLMKQLGYGDEYRYAHDEPDAYAAGEDYFPEELDPIPFYQPVPRGLELKI
GEKLNHLAKLDRLSPRQRRK