Protein Info for PfGW456L13_2651 in Pseudomonas fluorescens GW456-L13

Annotation: Cell division protein FtsK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 803 transmembrane" amino acids 27 to 46 (20 residues), see Phobius details amino acids 76 to 94 (19 residues), see Phobius details amino acids 114 to 136 (23 residues), see Phobius details amino acids 166 to 187 (22 residues), see Phobius details PF13491: FtsK_4TM" amino acids 23 to 193 (171 residues), 133.4 bits, see alignment E=1.4e-42 PF17854: FtsK_alpha" amino acids 308 to 408 (101 residues), 112.9 bits, see alignment E=1.5e-36 PF01580: FtsK_SpoIIIE" amino acids 418 to 628 (211 residues), 248.3 bits, see alignment E=1.2e-77 PF09397: FtsK_gamma" amino acids 737 to 797 (61 residues), 88.2 bits, see alignment 4.7e-29

Best Hits

Swiss-Prot: 90% identical to FTSK_PSEU2: DNA translocase FtsK (ftsK) from Pseudomonas syringae pv. syringae (strain B728a)

KEGG orthology group: K03466, DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family (inferred from 97% identity to pfo:Pfl01_3586)

Predicted SEED Role

"Cell division protein FtsK" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton or Bacterial RNA-metabolizing Zn-dependent hydrolases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QKI6 at UniProt or InterPro

Protein Sequence (803 amino acids)

>PfGW456L13_2651 Cell division protein FtsK (Pseudomonas fluorescens GW456-L13)
LKKSTAAPKPAVVPLWRQHLHYRLKEGALIAIGALCLFLMMALLTYGKDDPGWSHNSKID
DVQNFGGPAGSYSADILFMVLGYFAYIFPLLLAIKAYQIFRQRHEPWQWSGWLFSWRLIG
LVFLVLSGAALAHIHFHAATGLPAGAGGALGESLGELARNALNIQGSTLLFIALFLFGLT
VFTDLSWFKVMDITGKITLDLFELFQGAANRWWAARTERKQLVAQLREVDDRMDEVVAPT
VTDKREQAKVKERLIEREQALSKHMSEREKQVPPVIAPAPPKPAAPSKRVEKEKQAPLFV
DSAVEGTLPPISILDPAEKKQLNYSPESLAAVGHLLEIKLKEFGVEVAVDSIHPGPVITR
YEIQPAAGVKVSRISNLAKDLARSLAVTSVRVVEVIPGKTTVGIEIPNEDRQIVRFSEVL
STPEYDNFKSPVTLALGHDIGGKPVITDLAKMPHLLVAGTTGSGKSVGVNAMILSILFKS
GPEDAKLIMIDPKMLELSIYEGIPHLLCPVVTDMKDAANALRWSVAEMERRYKLMAKMGV
RNLSGFNAKVKEAQDAGEPLSDPLYKRESIHDEAPLLQKLPTIVVVVDEFADMMMIVGKK
VEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANIPTRMAFQVSSKIDSRTIIDQG
GAEQLLGHGDMLYMPPGTSLPIRVHGAFVSDDEVHRVVEAWKLRGAPEYNDDILNGVEEA
GSGFEGSSGGGDGDDPEADALYDEAVQFVLESRRASISAVQRKLKIGYNRAARMIEAMEM
AGVVTSMNTNGSREVLAPGPVRD