Protein Info for PfGW456L13_2562 in Pseudomonas fluorescens GW456-L13

Annotation: ABC-type protease exporter, ATP-binding component PrtD/AprD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 578 transmembrane" amino acids 21 to 44 (24 residues), see Phobius details amino acids 56 to 76 (21 residues), see Phobius details amino acids 145 to 174 (30 residues), see Phobius details amino acids 247 to 265 (19 residues), see Phobius details TIGR01842: type I secretion system ATPase" amino acids 17 to 557 (541 residues), 775.5 bits, see alignment E=1.4e-237 PF00664: ABC_membrane" amino acids 33 to 281 (249 residues), 52.7 bits, see alignment E=5.4e-18 PF00005: ABC_tran" amino acids 348 to 495 (148 residues), 93.6 bits, see alignment E=1.7e-30

Best Hits

Swiss-Prot: 56% identical to APRD_PSEAE: Alkaline protease secretion ATP-binding protein AprD (aprD) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K12536, ATP-binding cassette, subfamily C, bacterial HasD (inferred from 89% identity to ppg:PputGB1_3354)

Predicted SEED Role

"ABC-type protease exporter, ATP-binding component PrtD/AprD" in subsystem Protein secretion by ABC-type exporters

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QQ78 at UniProt or InterPro

Protein Sequence (578 amino acids)

>PfGW456L13_2562 ABC-type protease exporter, ATP-binding component PrtD/AprD (Pseudomonas fluorescens GW456-L13)
MPKQSSIRSELADALFRLRRSFYSLAAFSGVINVMMLTPAIYMLQVYDRALVSRNVTTLT
MLTVLVVGLFLLMSTLEMVRTRVLIRVGNCLDMDLNRRIFTAAFERNLNRAGGNPAQALQ
DLAQVRQFVTGNSLFAFFDAPWTPIYLLVAYLIHPILGLITLIGSLILVALAWLTEKATQ
KPLAEANQAALSSGQYANNNLRNAEVIEAMGMLPSISKRWYQSHLRILEMQTLASDRAAV
ISSTGRFVRITLQSLILGAGALLAIEGKITPGMMIACSILTGRALGPVEQVIASWKQLLG
CRSAWGRLNEMLQDFPRRPPSMSLQRPMGMLAVENVYAGAPGTTNTILRGVSFSLVPGES
LGIIGPSASGKSTLARLLVGVWPTQAGKVRLDGADIFNWNKGELGPWLGYLPQDVELFEG
TIADNIARFGEVDSEAVIRAAKITGVHEMILRFPQGYDTRLGTDGSPLSGGQKQRIALAR
ALYGEPNLIVLDEPNANLDDVGEKALVDALAELKGRGATVILISHRPNVLCAVDKVLMLR
DGGVQMLGTRDEVFAALRKASVIPAGASTPLASVKARE