Protein Info for PfGW456L13_2532 in Pseudomonas fluorescens GW456-L13
Annotation: 3-oxoadipate CoA-transferase subunit B (EC 2.8.3.6); Glutaconate CoA-transferase subunit B (EC 2.8.3.12)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
No protein families (PFam or TIGRFam), signal peptides, or transmembrane helices were found in this protein.
Best Hits
KEGG orthology group: K01040, glutaconate CoA-transferase, subunit B [EC: 2.8.3.12] (inferred from 70% identity to shl:Shal_2126)Predicted SEED Role
"3-oxoadipate CoA-transferase subunit B (EC 2.8.3.6); Glutaconate CoA-transferase subunit B (EC 2.8.3.12)" (EC 2.8.3.12, EC 2.8.3.6)
MetaCyc Pathways
- aromatic compounds degradation via β-ketoadipate (9/9 steps found)
- catechol degradation III (ortho-cleavage pathway) (6/6 steps found)
- superpathway of salicylate degradation (6/7 steps found)
- 3-oxoadipate degradation (2/2 steps found)
- toluene degradation III (aerobic) (via p-cresol) (7/11 steps found)
- 4-methylcatechol degradation (ortho cleavage) (4/7 steps found)
- L-glutamate degradation V (via hydroxyglutarate) (6/10 steps found)
- L-glutamate degradation XI (reductive Stickland reaction) (3/7 steps found)
- mandelate degradation to acetyl-CoA (10/18 steps found)
- superpathway of aromatic compound degradation via 3-oxoadipate (21/35 steps found)
- superpathway of aerobic toluene degradation (13/30 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.8.3.12, 2.8.3.6
Use Curated BLAST to search for 2.8.3.12 or 2.8.3.6
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A293QQ48 at UniProt or InterPro
Protein Sequence (262 amino acids)
>PfGW456L13_2532 3-oxoadipate CoA-transferase subunit B (EC 2.8.3.6); Glutaconate CoA-transferase subunit B (EC 2.8.3.12) (Pseudomonas fluorescens GW456-L13) MSTTDYSLAELMICAASEAWREDGEVLASGIGVIPRLAASLAMLTSNPQLLMTDSEAYMV AEPVPLGARKGYEPKRDSWMGFSRIFDNVWGGKRHALVGPTQIDRFGQANISCIGDYAKP KAQMLGVRGFPGNSISHANSFCVPSHNRRLFVEGEVDMVASVGYNPARLARGWSLNDIDI RLIITDLCVLDFQGPQRQMRIRSLHPGVTAAQVQDNTGFELHVPDDCPTTAAPTAEQLQL IQRLDPHNLRALQLKDNPPGQR