Protein Info for PfGW456L13_2455 in Pseudomonas fluorescens GW456-L13

Annotation: Histidine permease YuiF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 444 transmembrane" amino acids 9 to 37 (29 residues), see Phobius details amino acids 57 to 78 (22 residues), see Phobius details amino acids 99 to 118 (20 residues), see Phobius details amino acids 124 to 142 (19 residues), see Phobius details amino acids 151 to 176 (26 residues), see Phobius details amino acids 196 to 218 (23 residues), see Phobius details amino acids 239 to 258 (20 residues), see Phobius details amino acids 264 to 283 (20 residues), see Phobius details amino acids 295 to 314 (20 residues), see Phobius details amino acids 336 to 355 (20 residues), see Phobius details amino acids 362 to 391 (30 residues), see Phobius details amino acids 426 to 443 (18 residues), see Phobius details PF13726: Na_H_antiport_2" amino acids 8 to 93 (86 residues), 102.2 bits, see alignment E=2.1e-33 PF03553: Na_H_antiporter" amino acids 155 to 438 (284 residues), 274.3 bits, see alignment E=2e-85 PF06808: DctM" amino acids 192 to 394 (203 residues), 32.3 bits, see alignment E=7.7e-12

Best Hits

Swiss-Prot: 58% identical to Y2115_VIBPA: Uncharacterized membrane protein VP2115 (VP2115) from Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)

KEGG orthology group: K07084, (no description) (inferred from 96% identity to pfo:Pfl01_3769)

Predicted SEED Role

"Histidine permease YuiF"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QPB9 at UniProt or InterPro

Protein Sequence (444 amino acids)

>PfGW456L13_2455 Histidine permease YuiF (Pseudomonas fluorescens GW456-L13)
LYRGNEMNAVIAAVGIMLILSLSRVHVVIALIVGALVGGLTGGLGIEATLKAFNSGLGGG
ATVALSYALLGAFAVAIAKSGMAHALADKALAMVDRQHASGGGQVKWLLIGLLWVVAIAS
QNILPIHIAFIPLLVPPLLYVLTKLQLDRRLIACVMTFGLITPYMFLPVGFGNIFLNEIL
LANVARSGVDISGINVTHAMGIPALGMVAGLLIAFVSYRKKRVYDLAKIEQVEQVAVQYN
PLSLMVAGVAIAAAFIIQLLLDSMIIGALVGFLIFSVSGIVKWRDTDDLFTEGMKMMAMI
GFIMIAASGFAEVMKATGEVQTLVESSASYIDHSKGIGALLMLLVGLLVTMGIGSSFSTV
PILAAIFVPLCVQLGFSPLAIVCIVGTAGALGDAGSPASDSTLGPTSGLNIDGQHHHIWD
TVVPTFLHYNLPLLAFGWVAAMVL