Protein Info for PfGW456L13_2322 in Pseudomonas fluorescens GW456-L13

Annotation: Threonine and homoserine efflux system

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 274 transmembrane" amino acids 22 to 40 (19 residues), see Phobius details amino acids 51 to 71 (21 residues), see Phobius details amino acids 77 to 95 (19 residues), see Phobius details amino acids 102 to 119 (18 residues), see Phobius details amino acids 125 to 146 (22 residues), see Phobius details amino acids 158 to 179 (22 residues), see Phobius details amino acids 186 to 205 (20 residues), see Phobius details amino acids 217 to 237 (21 residues), see Phobius details amino acids 243 to 262 (20 residues), see Phobius details PF00892: EamA" amino acids 129 to 258 (130 residues), 64.5 bits, see alignment E=5.8e-22

Best Hits

Swiss-Prot: 57% identical to RHTA_SALTS: Threonine/homoserine exporter RhtA (rhtA) from Salmonella typhimurium (strain SL1344)

KEGG orthology group: None (inferred from 91% identity to pfo:Pfl01_3904)

MetaCyc: 57% identical to L-threonine/L-homoserine exporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-242; TRANS-RXN0-0244

Predicted SEED Role

"Threonine and homoserine efflux system"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QLZ7 at UniProt or InterPro

Protein Sequence (274 amino acids)

>PfGW456L13_2322 Threonine and homoserine efflux system (Pseudomonas fluorescens GW456-L13)
MASIQSGASLAKSMFSVVGPQGTTTLRLIFASVIMMLILRPWRAKFTAKSLRTVIVYGMA
LGGMNFLFYMSLQTVPLGIAVALEFTGPLAVAIYASRRAIDFLWIALAAAGLLLLIPTGE
TTTGIDLVGAGYALGAGVCWALYILFGQKAGADNGVQTAALGVMIAALFVAPIGIVHAGS
ALLSPSLIPIALGVAILSTALPYTLEMVALTRMPARTFGTLMSIEPAFGALSGLLFLHEY
LSLSQWMAIMCIILASVGATMTMSTSTRPAVAAD