Protein Info for PfGW456L13_2317 in Pseudomonas fluorescens GW456-L13

Annotation: Xaa-Pro aminopeptidase (EC 3.4.11.9)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 602 PF01321: Creatinase_N" amino acids 14 to 137 (124 residues), 43.5 bits, see alignment E=8.8e-15 PF16189: Creatinase_N_2" amino acids 156 to 311 (156 residues), 146.8 bits, see alignment E=1.2e-46 PF00557: Peptidase_M24" amino acids 316 to 529 (214 residues), 164 bits, see alignment E=8.4e-52 PF16188: Peptidase_M24_C" amino acids 542 to 602 (61 residues), 85.8 bits, see alignment 3e-28

Best Hits

KEGG orthology group: K01262, Xaa-Pro aminopeptidase [EC: 3.4.11.9] (inferred from 92% identity to pfo:Pfl01_3911)

Predicted SEED Role

"Xaa-Pro aminopeptidase (EC 3.4.11.9)" (EC 3.4.11.9)

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.9

Use Curated BLAST to search for 3.4.11.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QJL1 at UniProt or InterPro

Protein Sequence (602 amino acids)

>PfGW456L13_2317 Xaa-Pro aminopeptidase (EC 3.4.11.9) (Pseudomonas fluorescens GW456-L13)
MNTQLSINGSVPQRLAQTRELMSREGIHALLVPSADPHLSEYLPGYWQGRQWLSGFHGSV
GTLIVTPDFAGVWADSRYWEQATKELNGSGIDLVKLQPGQPGPLEWLAEQTPEGGVVAVD
GAVMAVASARTLGGKLEERGARLRTDIDLLNGVWSDRPGLPNEPIYQHLPPQATVSRGEK
LAKLRETLQARGADWHFIATLDDIAWLFNLRGGDVSFNPVFVSFALINQQQATLFVALSK
VSAELRAILERDGVTLRDYSEVATALRAVPSGASLQVDPARVTAGLLDNLDSGVKLIEGL
NPTTLAKSQKSLADAEHIRQAMEQDGAALCEFFAWLDSALGRERITELTIDEKLTAARER
RPDYVSLSFNTIAAFNANGAMPHYHATEEEHAVIEGDGLLLIDSGGQYLGGTTDITRMVA
VGTPTDEQKRDCTRVLKGVIALSRAQFPKGILSPLLDAIARAPIWAESVDYGHGTGHGVG
YFLNVHEGPQVIAYQAAPAPQTAMQPGMITSIEPGTYRPGRWGVRIENLAMNREAGKSEF
GEFLKFETLTLCPIDTRCLETSLLSEDEKQWFNAYHAEVRERLSPLVEGAALEWLNTRTA
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