Protein Info for PfGW456L13_231 in Pseudomonas fluorescens GW456-L13

Annotation: Selenoprotein O and cysteine-containing homologs

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 487 PF02696: SelO" amino acids 6 to 456 (451 residues), 498.3 bits, see alignment E=1.1e-153

Best Hits

Swiss-Prot: 90% identical to SELO_PSEPF: Protein adenylyltransferase SelO (selO) from Pseudomonas fluorescens (strain Pf0-1)

KEGG orthology group: None (inferred from 90% identity to pfo:Pfl01_0444)

MetaCyc: 51% identical to protein adenylyltransferase SelO (Escherichia coli K-12 substr. MG1655)
RXN0-7371 [EC: 2.7.7.108]

Predicted SEED Role

"Selenoprotein O and cysteine-containing homologs"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.108

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293PWG1 at UniProt or InterPro

Protein Sequence (487 amino acids)

>PfGW456L13_231 Selenoprotein O and cysteine-containing homologs (Pseudomonas fluorescens GW456-L13)
LKALDELTFDNRFDRLGDAFSAHVLPEPIDNPRLVVASPAAMALLDLDPSVAETPEFAEL
FSGHKLWADAIPRAMVYSGHQFGSYNPQLGDGRGLLLGEVYNEAGEHWDLHLKGAGQTPF
SRMGDGRAVLRSSIREFLASEALNALNIPTTRALCVIGSDTPVWREKQERAAMILRLAPS
HVRFGHFEYFYYTKRPEQQKELGDHVLAMHFPQCLEQPEPYLAMFREVVERNAELIAKWQ
AYGFCHGVMNTDNMSILGITFDFGPFAFLDDFDANFICNHSDDQGRYSFSNQVPIGQWNL
SALAQALTPFISVEALRETLGLYLPLFQAHYLDLMRRRLGLTTAEDDDQKLLENLLQLMQ
NSGVDYSLFFRRLGDQAPEQAITRLREDFVDLKGFDAWGELYVARGSREGTLDQEQRRQR
MHAVNPLYILRNYLAQNAIDAAQNGDYSEVRRLHAVLSNPFEEQPGMESYAERPPEWGKH
LEISCSS