Protein Info for PfGW456L13_2301 in Pseudomonas fluorescens GW456-L13

Annotation: Pyoverdin biosynthesis protein PvdH, L-2,4-diaminobutyrate:2-oxoglutarate aminotransferase (EC 2.6.1.76)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

Swiss-Prot: 63% identical to RHBA_RHIME: Diaminobutyrate--2-oxoglutarate aminotransferase (rhbA) from Rhizobium meliloti (strain 1021)

KEGG orthology group: K00836, diaminobutyrate-2-oxoglutarate transaminase [EC: 2.6.1.76] (inferred from 92% identity to pfo:Pfl01_3932)

MetaCyc: 86% identical to L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase monomer (Pseudomonas aeruginosa PAO1)
Diaminobutyrate--2-oxoglutarate transaminase. [EC: 2.6.1.76]

Predicted SEED Role

"Pyoverdin biosynthesis protein PvdH, L-2,4-diaminobutyrate:2-oxoglutarate aminotransferase (EC 2.6.1.76)" in subsystem Siderophore Pyoverdine (EC 2.6.1.76)

MetaCyc Pathways

ectoine biosynthesis (3/5 steps found)
pyoverdine I biosynthesis (7/11 steps found)
norspermidine biosynthesis (3/6 steps found)
ectoine degradation (1/4 steps found)
superpathway of polyamine biosynthesis III (3/8 steps found)
rhizobactin 1021 biosynthesis (1/7 steps found)
baumannoferrin biosynthesis (1/11 steps found)

KEGG Metabolic Maps

Glycine, serine and threonine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.6.1.76

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QND4 at UniProt or InterPro

Protein Sequence (466 amino acids)

>PfGW456L13_2301 Pyoverdin biosynthesis protein PvdH, L-2,4-diaminobutyrate:2-oxoglutarate aminotransferase (EC 2.6.1.76) (Pseudomonas fluorescens GW456-L13)
MSVATNLIEEQPATSAETLYQFNESPLLARQSRQESNARSYPRRIPLALKRAKGIYVEDV
EGRTFIDCLAGAGTLALGHNHPVVIEAIQQVLADELPLHTLDLTTPVKDRFVQDLFGLLP
PALAAEAKIQFCGPTGTDAVEAALKLVRTATGRSTVISFQGGYHGMSQGALSLMGSLGPK
KPLGALLGSGVQFMPYPYDYRCPFGLGGAQGVKANLSYLENLLNDPEAGVQLPAAVIVEV
VQGEGGVIPADLDWLRGVRRITEQAGVALIVDEIQSGFARTGKMFAFEHAGIIPDVVVMS
KAIGGSLPLAVVVYRDWLDTWLPGAHAGTFRGNQMAMAAGCAVMRYLVEHKVCEHAAAMG
ERLAEHLRILQRDFPQLGDIRGRGLMLGVELVDPTGALDAQGHPPAFARLAPLVQRECLK
RGLILELGGRHGAVVRFLPPLVITAAQIDRVAEIFGRALAAATANP