Protein Info for PfGW456L13_2297 in Pseudomonas fluorescens GW456-L13

Annotation: Cytochrome c-type biogenesis protein CcmG/DsbE, thiol:disulfide oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 284 transmembrane" amino acids 6 to 30 (25 residues), see Phobius details amino acids 42 to 65 (24 residues), see Phobius details amino acids 80 to 97 (18 residues), see Phobius details amino acids 109 to 130 (22 residues), see Phobius details PF01790: LGT" amino acids 3 to 99 (97 residues), 34.1 bits, see alignment E=3.8e-12 PF08534: Redoxin" amino acids 132 to 257 (126 residues), 60.3 bits, see alignment E=3.8e-20 PF00578: AhpC-TSA" amino acids 133 to 245 (113 residues), 58 bits, see alignment E=1.9e-19

Best Hits

KEGG orthology group: None (inferred from 87% identity to pfo:Pfl01_3937)

Predicted SEED Role

"Cytochrome c-type biogenesis protein CcmG/DsbE, thiol:disulfide oxidoreductase" in subsystem Biogenesis of c-type cytochromes or Periplasmic disulfide interchange

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QJL0 at UniProt or InterPro

Protein Sequence (284 amino acids)

>PfGW456L13_2297 Cytochrome c-type biogenesis protein CcmG/DsbE, thiol:disulfide oxidoreductase (Pseudomonas fluorescens GW456-L13)
MLTFTLGTFAIALNHLLLISALALATFVGWRVAKRGGENPESVLFSLFLMGMLAARISFV
AAYWVHYRNDPWQVIDLRDGGFLAWPGVVVVLLATLYRGWRRPGLRRPLGFGVASGLAFW
LLATFSLSIYEQGTRLPEIILRNAAGETVQLADYKGGPLVINLWATWCPPCRREMPVLEN
AQQQRPDLTFLFVNQSESMQSVAIFLETQGLSLSNVLFDGSGRLSQAVGSMALPTTLFYN
PEGRLLGSHLGELSEASLARALENFDTVPATSSRKLPCPASATC