Protein Info for PfGW456L13_2165 in Pseudomonas fluorescens GW456-L13

Annotation: Lipid A export ATP-binding/permease protein MsbA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 605 transmembrane" amino acids 33 to 54 (22 residues), see Phobius details amino acids 85 to 108 (24 residues), see Phobius details amino acids 167 to 186 (20 residues), see Phobius details amino acids 192 to 210 (19 residues), see Phobius details amino acids 293 to 318 (26 residues), see Phobius details PF00664: ABC_membrane" amino acids 70 to 322 (253 residues), 94.2 bits, see alignment E=1.2e-30 PF00005: ABC_tran" amino acids 384 to 532 (149 residues), 107.2 bits, see alignment E=1.1e-34

Best Hits

KEGG orthology group: K06148, ATP-binding cassette, subfamily C, bacterial (inferred from 92% identity to pfo:Pfl01_4088)

Predicted SEED Role

"Lipid A export ATP-binding/permease protein MsbA" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QP39 at UniProt or InterPro

Protein Sequence (605 amino acids)

>PfGW456L13_2165 Lipid A export ATP-binding/permease protein MsbA (Pseudomonas fluorescens GW456-L13)
VHDLPDDVAPAKRVDRLSWAEIRRLALHHKKSLWIANGVAVLATLCSVPIPLLLPLLVDE
VLLGHGDAALKIMNHVLPEGWQKAAGYIGLMLLVTLTLRCTALLFNVVQAKLFAGLAKDI
VYRIRIRLIERLKGISLGEYESLGSGTVTTHLVTDLDTLDKFVGETLSRFLVAMLTLVGT
AGILMWMHWQLALLILLFNPLVIYATVQLGKRVKHLKKLENDSTSRFTQALTETLDAIQE
VRAGNRQGFFLGRLGQRARDVRDYAVNSQWKTDASNRASGLLFQFGIDIFRAAAMLTVLF
SDLSIGQMLAVFSYLWFMIGPVEQLLNLQYAYYAAGGALSRINELLSRADEPQYPGGIDP
FVGRETVGLEVQGLSFGYGDELVLNQMNLSIAPGEKVAIVGASGGGKSTLVQLLLGLYTP
LAGTIRFGGSTQQEIGLETVRENVAVVLQHPALFNDTIRANLTMGRERSDEACWQALEIA
QLHGTVRDLPKGLDSIVGRSGVRLSGGQRQRLAIARMVLAEPKVVILDEATSALDAATEY
NLHQALARFLSNRTTLIIAHRLSAVKQADRVLVFDGGQIAEDGDHQQLIADGGLYAKLYG
HLQRL