Protein Info for PfGW456L13_1941 in Pseudomonas fluorescens GW456-L13

Annotation: Magnesium and cobalt transport protein CorA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 340 transmembrane" amino acids 279 to 301 (23 residues), see Phobius details amino acids 314 to 334 (21 residues), see Phobius details PF01544: CorA" amino acids 48 to 332 (285 residues), 165 bits, see alignment E=1.3e-52

Best Hits

KEGG orthology group: K03284, metal ion transporter, MIT family (inferred from 92% identity to pba:PSEBR_a4346)

Predicted SEED Role

"Magnesium and cobalt transport protein CorA" in subsystem Campylobacter Iron Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293PYT7 at UniProt or InterPro

Protein Sequence (340 amino acids)

>PfGW456L13_1941 Magnesium and cobalt transport protein CorA (Pseudomonas fluorescens GW456-L13)
MNHSIDQSHRDTDLFGLLYVFSFRPGEAGREINSAEALQYLQQPQSDEQFLWLHLNLAHA
ACERWMKSHLELPEEFFEALHEGSRSTRIEHVDSALLAVVNDVVFNLSNMVSSDVSTLWV
CARSQLIISARLQPLHSVDKLRSSVKARECFRSPLELLVHLLRDQGEVLTQIVRKTSQSV
DQIEDQLLSSRLSTNRAELGANRRVLVRLQRLLALEPGSLLRLLNRPPQWLQKEDVKELR
KSTEEFALIINDLTALGERIKLLQEEIAANINEQTNRTLFTLTVVTVLALPINIIAGFFG
MNVGGIPLADDPQGFWILVALVATFTVIAGRWAFRKQQDY