Protein Info for PfGW456L13_1897 in Pseudomonas fluorescens GW456-L13

Updated annotation (from data): ABC transporter for D-Galactose and D-Glucose, ATPase component
Rationale: Specific phenotype on D-Galactose; L-Lysine; L-Aspartic Acid. The nitrogen source phenotypes for aspartate and lysine are with glucose as the carbon source. May also transport fructose.
Original annotation: Glucose ABC transporter, ATP-binding subunit (EC 3.6.3.-)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 386 PF00005: ABC_tran" amino acids 21 to 163 (143 residues), 117.2 bits, see alignment E=2.3e-37 PF17912: OB_MalK" amino acids 237 to 291 (55 residues), 50.4 bits, see alignment 8.5e-17 PF08402: TOBE_2" amino acids 284 to 357 (74 residues), 40.7 bits, see alignment E=5.3e-14 PF03459: TOBE" amino acids 303 to 356 (54 residues), 34.5 bits, see alignment 4.7e-12

Best Hits

KEGG orthology group: K02023, multiple sugar transport system ATP-binding protein (inferred from 91% identity to pfo:Pfl01_4367)

Predicted SEED Role

"Glucose ABC transporter, ATP-binding subunit (EC 3.6.3.-)" (EC 3.6.3.-)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293PYR7 at UniProt or InterPro

Protein Sequence (386 amino acids)

>PfGW456L13_1897 ABC transporter for D-Galactose and D-Glucose, ATPase component (Pseudomonas fluorescens GW456-L13)
MATLELRNVNKTYGPGLPDTLKNIELKIDDGEFLILVGPSGCGKSTLMNCIAGLETISGG
AILVDDADISGMSPKDRDIAMVFQSYALYPTMSVRDNIAFGLKIRKMPTAEIDEEVARVS
KLLQIEHLLSRKPGQLSGGQQQRVAMGRALARRPKIYLFDEPLSNLDAKLRVEMRTEMKL
MHQRLKTTTVYVTHDQIEAMTLGDKVAVMKDGIIQQFGTPKDIYNNPANLFVASFIGSPP
MNFIPLRLQRKDGRLLALLDSGQARCELPLGMQDAGLEDREVILGIRPEQIILANGEANG
LPTIRAEVQVTEPTGPDTLVFVNLNDTKVCCRLAPDVAPAVGETLTLQFDPAKVLLFDAK
TGERLGVAGVPKAEAHADNVAQFKGR