Protein Info for PfGW456L13_185 in Pseudomonas fluorescens GW456-L13

Annotation: Predicted hydroxymethylpyrimidine transporter CytX

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 430 transmembrane" amino acids 27 to 49 (23 residues), see Phobius details amino acids 56 to 77 (22 residues), see Phobius details amino acids 97 to 118 (22 residues), see Phobius details amino acids 141 to 163 (23 residues), see Phobius details amino acids 170 to 188 (19 residues), see Phobius details amino acids 205 to 225 (21 residues), see Phobius details amino acids 237 to 262 (26 residues), see Phobius details amino acids 270 to 290 (21 residues), see Phobius details amino acids 317 to 335 (19 residues), see Phobius details amino acids 341 to 362 (22 residues), see Phobius details amino acids 374 to 394 (21 residues), see Phobius details amino acids 402 to 421 (20 residues), see Phobius details PF02133: Transp_cyt_pur" amino acids 14 to 368 (355 residues), 86 bits, see alignment E=1.3e-28 TIGR02358: putative hydroxymethylpyrimidine transporter CytX" amino acids 24 to 415 (392 residues), 435 bits, see alignment E=1.4e-134

Best Hits

KEGG orthology group: K03457, nucleobase:cation symporter-1, NCS1 family (inferred from 93% identity to pfo:Pfl01_0493)

Predicted SEED Role

"Predicted hydroxymethylpyrimidine transporter CytX" in subsystem Thiamin biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QIR3 at UniProt or InterPro

Protein Sequence (430 amino acids)

>PfGW456L13_185 Predicted hydroxymethylpyrimidine transporter CytX (Pseudomonas fluorescens GW456-L13)
LSIQPSTYSPDIAVPTDKRVFGGRDLFSLWFSLGIGLMVLQTGALLAPGLGLSGSLLAIF
LGTLVGVLLLAAVGVIGSDTGLSSMAALKLSLGAKGASLPAVLNLLQLIGWGSFEIIVMR
DAASLLGAKAFNEGSLLSNPVLWTLFFGALATLLAVSGPLTFVRQILRKWGIWLLLAACV
WLTWNLFAKADLAALWAQAGDGSMPFAVGFDIAIAMPLSWLPLIADYSRFGKRAKNVFGG
TAIGFFIGNFWLMSLGVAYTLAFAPSGEVNALLLALAGAGLGIPLLLILLDESENAFADI
HSAAVSSGILLRAKVEHLALAIGVICTLIALLAPLAQYQNFLLLIGSVFAPLFGVVLVDH
FILRKRSGLVASAALRWPALLAWLGGVSTYHLLANLYPDVGATLPALIVAGLLQLVLGRA
FSYGRETARA