Protein Info for PfGW456L13_1838 in Pseudomonas fluorescens GW456-L13

Annotation: Sensory box histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 684 transmembrane" amino acids 21 to 48 (28 residues), see Phobius details amino acids 161 to 185 (25 residues), see Phobius details PF00672: HAMP" amino acids 191 to 240 (50 residues), 35.2 bits, see alignment 3.1e-12 TIGR00229: PAS domain S-box protein" amino acids 294 to 409 (116 residues), 28.7 bits, see alignment E=6.1e-11 PF00989: PAS" amino acids 295 to 400 (106 residues), 44.2 bits, see alignment E=4.4e-15 PF08448: PAS_4" amino acids 300 to 403 (104 residues), 37 bits, see alignment E=9.1e-13 PF02518: HATPase_c" amino acids 558 to 670 (113 residues), 81.8 bits, see alignment E=1.2e-26

Best Hits

KEGG orthology group: K00936, [EC: 2.7.3.-] (inferred from 93% identity to pfo:Pfl01_4423)

Predicted SEED Role

"Sensory box histidine kinase"

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QSH1 at UniProt or InterPro

Protein Sequence (684 amino acids)

>PfGW456L13_1838 Sensory box histidine kinase (Pseudomonas fluorescens GW456-L13)
LSAINPMPLRQRLENLPVGQKLLAALLVLMVTVLLVANLTFISAAYYISQESMAPQALQT
IGRLISNPSLASEALASPQSAERLLNELNSYSPLRAAALYDGKGERLAQLQHGDNLELPK
RFRHIEDWQATEFRTNQVIPLPRTGAAPGHLLLVATSELPVAFYTGTLTASLGILIFSVL
LWLIIARQIKRLITRPIHQLEELSRQVTREENYALRASRGNHDEIGSLAEAFNTMLSRIE
AREQQLKRARDDSQAAYDQAQGLAEETRHTNRKLELEVQVRSKIEKKLTGFQNYLNSIID
SMPSALIALDEQLYVTQWNQEASALSGTRLDEALNQPIFLAFEPLKPFLPQLKETVEQHT
VAKIERVTWLKDDEPRHYALTFYPLMGGAGRGVVIRIDDITQRLSLEEMMVQSEKMLSVG
GLAAGMAHEINNPLGAILHNVQNIRRRLSPDLPKNLEVAEQAGIELTTVNQYLQVREVPQ
LLDGIQQAGARAAKIVTHMLSFSRRSTRQMAPCDLPALIDQAVEIAGNDFDLAIGFDFKG
QAIIRQFDPALGPVPGTANELEQVLLNLLKNAAQAIHQREDDSEPGRIILRTRLNPPWAE
IQVEDNGIGMSESVRKRTFEPFFTTKEIGQGTGLGLSVSYFIVTNNHKGQMEVQSTLGQG
TCFTLRLPLASTPPVSQQLNLLSR