Protein Info for PfGW456L13_1833 in Pseudomonas fluorescens GW456-L13

Annotation: Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 911 PF07517: SecA_DEAD" amino acids 6 to 401 (396 residues), 432.6 bits, see alignment E=2.1e-133 TIGR00963: preprotein translocase, SecA subunit" amino acids 28 to 818 (791 residues), 1095.4 bits, see alignment E=0 PF00270: DEAD" amino acids 96 to 216 (121 residues), 25.3 bits, see alignment E=3.6e-09 PF01043: SecA_PP_bind" amino acids 232 to 358 (127 residues), 121.4 bits, see alignment E=8.4e-39 PF21090: P-loop_SecA" amino acids 417 to 614 (198 residues), 297.8 bits, see alignment E=1.2e-92 PF07516: SecA_SW" amino acids 617 to 830 (214 residues), 241 bits, see alignment E=3.7e-75 PF02810: SEC-C" amino acids 891 to 908 (18 residues), 35.2 bits, see alignment (E = 2.6e-12)

Best Hits

Swiss-Prot: 81% identical to SECA_AZOVD: Protein translocase subunit SecA (secA) from Azotobacter vinelandii (strain DJ / ATCC BAA-1303)

KEGG orthology group: K03070, preprotein translocase subunit SecA (inferred from 81% identity to avn:Avin_13340)

Predicted SEED Role

"Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A293QN93 at UniProt or InterPro

Protein Sequence (911 amino acids)

>PfGW456L13_1833 Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1) (Pseudomonas fluorescens GW456-L13)
MFAPLLKKLFGSKNEREVKRMLKTVQLVNAFEEQMVALSDDQLRAKTSEFKARIAKGESL
DKLLPEAFAVAREAGKRVMGMRHFDVQLIGGMTLHEGMIAEMRTGEGKTLVATLGVYLNA
LSGNGVHVVTVNDYLARRDANWMRPLYEFLGLTVGVVTPFQPPEEKRAAYAADITYGTNN
EFGFDYLRDNMAFSMEEKFQRELNFAVIDEVDSILIDEARTPLIISGQAEDSSKLYIEVN
KLIPQLKLHVEEVEGEVTQAGHFTVDEKTRQVELNEAGHQYVEETLTRIGLLAEGESLYS
AHNLSLLTHVYAGLRAHKLFHRNVEYIVQDGQVVLVDEHTGRTMPGRRLSEGLHQAIEAK
ENLNIQAESQTLASTTFQNYFRLYNKLSGMTGTADTEAFEFHQIYGLQVMVIPPNKPLAR
KDYNDLVFLTADEKYAAIVADIKESMAAGRPVLVGTATIETSEHMSSLLVKEGIEHKVLN
AKFHEKEAEIIAQAGRPGALTIATNMAGRGTDILLGGNWEVEVASLENPTPEQIAQIKAD
WQKRHQQVLESGGLQVIASERHESRRIDNQLRGRAGRQGDAGSSRFYLSLEDSLMRIFAS
DRVKNFMKALGMQPGEAIEHRMVTNAIEKAQRKVEGRNFDIRKQLLEFDDVNNEQRKVIY
HMRNTLLAADNIGETIADFRQDVLEATVSAHIPPQSLPEQWDVAGLEAALQSDFGVALPI
QQWLDEDDHLYEETLREKLMQELIAAYNEKEDQAGAEALRTFEKQIVLRVLDDLWKDHLS
TMDHLRHGIHLRGYAQKNPKQEYKRESFTLFSELLDSIKRDSIRVLSHVQVRREDPIEEE
QRLRQEAEALAARMQFLHEEAPGLEQPEALGEEIDVALAAAPVRNEQKLGRNELCYCGSG
KKFKHCHGQIQ